treats Giardia, Entamoeba, Trichomonas (vaginitis)
antibacterial and Antiprotozoal agent
-forms toxic free radical metabolites in the bacterial cell that damages DNA
what is trimethoprim?
describe its mechanism of action
"Try me"😎>> nvr mind i got a UTI -.-
Used in combination with Sulphonamides
-treatment of UTI,shigella, salmonella, it interferes w/ folic acid synthesis, which is responsible in NUCLEIC ACID synthesis.
side effects: megoblastic anemia, leukopenia, granulocytopenia
(TMP= Treats Marrow Poorly)
**A potent inhibitor of bacterial dihydrofolate reductase. Leading to a decreased availability of the tetrahydrofolate cofactors required for purine, pyrimidine, and amino acid synthesis
effective against multidrug resistent organisms!
Be aware: if weyre trying to treat staph aureus!( which is in the blood stream) We give it to them IV
but in Cdiff>> give them orally!
what do the terms Bacteriostatic and bacteriosidal mean WHEN ADMINISTERING A DRUG?
Bacteriostatic= Inhibit the growth of the bacteria (then immune system finsihes the dirty work)
Bacteriosidal= KILL the bacteria in the presence of an ineffective immune system
GIVE BACTERIOSTATIC ONLY IN SOMEONE WITH AN EFFECTIVE IMMUNE SYSTEM!
under what class?
(lies under Cephalocporin class)
B-lactam drugs that inhibit cell wall synthesis
has good activity in the CSF
-MENINGITIS, Gonirrhea, disseminated lyme disease
– Active against staphylococci & streptococci
Must know this!
its quite cocky!
flucloxacillin has activity against beta-lactamase-producing organisms such as Staphylococcus aureus[
inhibits cell wall synthesis
by inhibiting cross links of peptidoglycans!
flucloxacillin vs Penicillin
– Mainly active against streptococci >> Penicillin
-– Active against staphylococci & streptococci >Flucloxacillin
microbial therpy summary
List 4 indications for Tetracycline use
Non-pneumonic chest infections
Skin/soft-tissue infection with penicillin allergy
Pelvic Inflammatory Disease
which antibiotic class inhbits cell wall synthesis by inhibiting peptidoglycan cross linking?
Cepaholsphorins, pencillins, carbapenems
"i went to Canada and got a Flu"
Inhibit cell-membrane synthesis
to treat Candida
can be used orally and IV
used for oral and vaginal thrush
can be used also in imuunocompirompised patients
What do we give against Influenza A & B ?
What is aciclovir?
Antiviral agent used for herpes and varicella zoster.
Active in atypical pathogens in pneumonia
– Active against chlamydia & some protozoa
– Shouldn’t be given to children <12 years
name the antibiotic Tetracycline & doxycycline
If u have cellulotis and u dint know what the cause is what anitbiotic do u give?
what does this amntibiotic do?
U had a UTI infection whith this strain shown?
what is the bacteria? What tyore? How do u treat it? Mechanicsm of acrion
Gram negative bacillii
This is a case of tonsilitis!>> what bacteria causes it? How do u treat it? What is the emchanism of axtion