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Flashcards in Main types of antibiotics Deck (19):
1

Metronidazole

GET 

treats Giardia, Entamoeba, Trichomonas (vaginitis)

 

antibacterial and Antiprotozoal agent 

-forms toxic free radical metabolites in the bacterial cell that damages DNA

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2

what is trimethoprim?

describe its mechanism of action

"Try me"😎>> nvr mind i got a UTI -.-

Used in combination with Sulphonamides

 

-treatment of UTI,shigella, salmonella, it interferes w/ folic acid synthesis, which is responsible in NUCLEIC ACID synthesis.

 

side effects: megoblastic anemia, leukopenia, granulocytopenia 

(TMP= Treats Marrow Poorly)

 

 

 

 

**A potent inhibitor of bacterial dihydrofolate reductase. Leading to a decreased availability of the tetrahydrofolate cofactors required for purine, pyrimidine, and amino acid synthesis

3

Vancomycin

Glycopeptide!

effective against multidrug resistent organisms!

Be aware: if weyre trying to treat staph aureus!( which is in the blood stream)  We give it to them IV

 

but in Cdiff>> give them orally!

 

 

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4

what do the terms Bacteriostatic and bacteriosidal mean WHEN ADMINISTERING A DRUG?

Bacteriostatic= Inhibit the growth of the bacteria (then immune system finsihes the dirty work)

Bacteriosidal= KILL the bacteria in the presence of an ineffective immune system

 

GIVE BACTERIOSTATIC ONLY IN SOMEONE WITH AN EFFECTIVE IMMUNE SYSTEM!

5

Ceftriaxone 

under what class?

(lies under Cephalocporin class)

B-lactam drugs that inhibit cell wall synthesis

Gram -

has good activity in the CSF 

-MENINGITIS, Gonirrhea, disseminated lyme disease

6

Flucloxacillin

– Active against staphylococci & streptococci 

 

Must know this!

its quite cocky!

 

flucloxacillin has activity against beta-lactamase-producing organisms such as Staphylococcus aureus[

7

Penicillin mechanism

inhibits cell wall synthesis 

by inhibiting cross links of peptidoglycans!

8

flucloxacillin vs Penicillin

– Mainly active against streptococci >> Penicillin 

-– Active against staphylococci & streptococci >Flucloxacillin 

9

microbial therpy summary

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10

List 4 indications for Tetracycline use

Non-pneumonic chest infections 
Skin/soft-tissue infection with penicillin allergy 
Chalmydia 
Pelvic Inflammatory Disease

11

which antibiotic class inhbits cell wall synthesis by inhibiting peptidoglycan cross linking?

Cepaholsphorins, pencillins, carbapenems

12

Fluconazole

"i went to Canada and got a Flu"

Inhibit cell-membrane synthesis 

to treat Candida

can be used orally and IV

used for oral and vaginal thrush

can be used also in imuunocompirompised patients

13

What do we give against Influenza A & B ?

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14

What is aciclovir?

Antiviral agent used for herpes and varicella zoster.

15

Active in atypical pathogens in pneumonia

–  Active against chlamydia & some protozoa

–  Shouldn’t be given to children <12 years 

 

 

name the antibiotic Tetracycline & doxycycline 

16

Amoxillin?

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17

If u have cellulotis and u dint know what the cause is what anitbiotic do u give?

what does this amntibiotic do?

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Flucoxcillin

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18

U had a UTI infection whith this strain shown?

what is the bacteria? What tyore? How do u treat it? Mechanicsm of acrion

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Gram negative bacillii

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19

This is a case of tonsilitis!>> what bacteria causes it? How do u treat it? What is the emchanism of axtion

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