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*Part II Supplemental > Malignant Neoplasm > Flashcards

Malignant Neoplasm Flashcards

1
Q

Multiple Myeloma AKA

A

Plasma Cell Sarcoma

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2
Q

> 50, Cachexia, weight loss, anemia, MC primary malignancy of bone, malignant proliferation of plasma cell infiltrating the bone marrow

A

MM

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3
Q

Multiple dark densities that are similar in size (PUNCHED OUT LESION).
Can cause pathological collapse (Vertebral Plana)

A

MM

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4
Q

Rain drop skull

A

MM

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5
Q

Labs: 1. M Spike on ImmunoElectroPhoresis

  1. Reversal of the albumin/ globulin ratio
  2. Bence Jones Protein
  3. Elevated ESR

Special test: Bone scan: Cold

A

MM

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6
Q

MC malignant tumor of the bone

A

Metastatic Disease (Lytic and Blastic)

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7
Q

> 40 YO, recent unexplained weigh loss, skeletal pain worse at night.
Lab: Alkaline phosphatase
Special test: Bone scan

A

Lytic mets

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8
Q

Trabeculae reabsorbed turns the bone darker in color. MOTH eaten or permeative pattern of destruction.
“EATS” away pedicles of bone
“Swiss Cheese” appearance in skull

A

Lytic Mets

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9
Q

MC metastasis at age 20-40.

Ivory white vertebrae with ANTERIOR body SCALLOPING

A

Hodgkin disease

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10
Q

Unilateral hilar lymphadenopathy in Caucasian males seen on PA Chest

A

Hodkin

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11
Q

Need biopsy to confirm (REED STERNBERG cell)

A

Hodgkin

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12
Q

> 40 YO, IVORY WHITE vertebrae, no cortical thickening or bone enlargement.
Lab: Increase Alkaline phospatase
Special test: Bone Scan

A

Blastic Mets

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13
Q

Paget’s AKA

A

Osteotitis Deformans

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14
Q

Males, >50 YO, causes cortical thickening, PICTURE Frame vertebrae, Increased bone density, coarsened trabeculae, bone expansion and BOWING DEFORMITY

A

Paget’s

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15
Q

Stages of Paget

A
  1. Lytic or destructive
  2. Combined
  3. Sclerotic
  4. Malignant (Osteosarcoma)
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16
Q

Labs for Paget

A

Incerased Alkaline Osteophosphatase

Special Test: Bone Scan

17
Q

> 40 YO, creates spiculated/ sunburst periosteal reaction of bone

A

Chondrosarcoma or Fibrosarcoma

18
Q

10-25 YO MC found on Diaphysis of LONG BONE

Permeative lesion that causes multi-parallel ONION SKIN (laminated) type of periosteal reaction

A

Ewing’s Sarcoma

19
Q

Codman’s triangle
Bone expansion
Saucerization

A

Ewing’s Sarcoma

20
Q

> 40 YO, Eberrant notochordal cell tumor.

MC Found in sacrum, 2nd MC location is skull

A

Chordoma

21
Q

Increase alkaline phosphatase test

A

Lytic Mets
Blastic Mets
Paget
Osteosarcoma

22
Q

MC malignancy found in children

Age group 10-30

A

Osteosarcoma

23
Q

Causes periosteal reaction that is spiculated/ radiating/ sunburst in appearance
Lab: Increased alkaline phosphatase
Special test: Bone scan

A

Osteosarcoma

*Part II Supplemental (28 decks)

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