Flashcards in March 17 test 2 Deck (14):
What are the MAOi's that can cause hypertensive crisis with ingestion of tyramine products?
MAO Takes Pride In Shanghai
What drug is used for Primary adrenal insufficiency--addison disease because it has mineralocorticoid activity?
What is the largest affect seen with the Fibrates?
Major decrease in TGs
What is the mechanism of action of the TCAs?
Block reuptake of NE and 5-HT
What antireflux drug class is associated with markedly elevated gastrin serum levels and risk of atrophic gastritis?
What is the mechanism of action of amantadine?
M2 protein inhibitor that prevents viral uncoating
--used for prophylaxis of the flu A
What is the MOA of Cromolyn sodium and what is it used for?
Prevents mast cell degranulation and is used for asthma prophylaxis
Recombinant IL-2--Aldesleukin is used for what?
Renal cell carcinoma
What oral hypoglycemic drugs are associated with a disulfiram-like effect when taken with ETOH?
First generation Sulfonylureas--Chlorpropamide and tolbutamide
What is the mechanism of action of Bleomycin?
Induces free radical formation--breaks in DNA strands
What protease inhibitor used for HIV can cause nephrotoxicity and hematuria?
What is the MOA of Doxorubicin and Daunorubicin?
Generate free radials and intercalate in DNA--breaks in DNA
Why should pts
Risk of toxic megacolon