March 19 test 1 Flashcards Preview

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Flashcards in March 19 test 1 Deck (15):
1

What are the 2 viruses in the reovirus family?

Coltivirus--Colorado tick fever
Rotavirus--#1 cause of fatal diarrhea in children

2

Hypercalcemia of malignancy is most commonly associated with what cancer?

Squamous cell carcinoma of the lung

3

What HLA is associated with MS and what other diseases are associated with this HLA?

HLA-DR2

Hay fever
SLE
Goodpasture

4

What is seen on CT of an epidural hematoma and what is causing this?

Biconvex (lentiform) hyper dense blood collection

Caused by rupture of middle meningeal artery --often secondary to skull fracture

5

What is seen on CT of a subdural hematoma and what is causing this?

Crescent-shaped hemorrhage--crosses suture lines

Caused by rupture of bridging veins --trauma, cerebral atrophy, elderly, alcoholism, and shaken babies

6

When should nitazoxanide be used to tx cryptosporidium?

In immunocompetent hosts

7

What vasculitis is associated with transmural inflammation of the arterial wall with fibrinoid necrosis?

Polyarteritis nodosa

Associated with HBV infection

8

What vasculitis is associated with polymyalgia rheumatica?

Giant cell (temporal) arteritis

9

Hyperinsulinemia/insulin resistance is associated with what female disorder?

PCOS

10

What is the major difference btw IgA nephropathy and post-strep GN?

Time frame--IgA (Berger) occurs 2-3 days after URI and post-strep occurs several wks post strep infection

11

What is seen on brain biopsy of pt with Lewy body dementia?

a-synuclein aggregates --primarily in cortex

12

What electrolyte abnormalities are present in rhabdomyolysis, which can occur with neuroepileptic malignant syndrome?

Hyperkalemia--due to cell lysis and release of K
Hyperuricemia
Hyperphosphatemia
Hypocalcemia

13

Does osteoporosis have any gross metabolic abnormalities?

No Ca, phosphorus, Alkphos, and Mg--normal

14

Why is bleeding time normal in pts with hemophilia?

Bleeding time only measures platelet function and platelets are normal with hemophilia

15

Weil-Felix is used for dx of what disease?

Rickettsia spp.