March 21 test 1

Question 1

What can cause malignant hyperthermia?

Answer 1

Inhaled anesthetics– Fluranes

Succinylcholine

Question 2

Vasculitis associated with HepB infection and has transmural inflammation of the arterial wall with fibrinoid necrosis?

Answer 2

Polyarteritis nodosa

• Presents in younger pt with fever, weight loss, malaise, HA, abd pain and melena
• Also, HTN, Neurologic dysfunction, cutaneous eruptsions, and renal damage

Question 3

Peripheral blood smear of pt with DIC is most likely to show what type of RBCs?

Answer 3

Schistocytes due to microangiopathic hemolytic anemia

Question 4

What is another name for acid-fast staining used for dx of Mycobacteria, Nocardia, and Cryptosporidium?

Answer 4

Ziehl-Neelsen stain–carbol fuchsin

Question 5

What are the risk factors for the development of Neonatal respiratory distress syndrome?

Answer 5

Prematurity
Maternal DM–due to increased fetal insulin
C-section–decreased release of fetal glucocorticoids

Question 6

Dermatitis herpetiformis is associated with what disease?

Answer 6

Celiac disease

Question 7

Pt with normal fluency and comprehension but defect in repetition suffers from damage to what?

Answer 7

Arcuate fasciculus –white matter that connects wernicke to brocas

Question 8

What pediatric brain tumor has homer-wright rosettes/pseudorosettes–small blue cells?

Answer 8

Medulloblastoma

Question 9

Presents as localized, single group of nodes and is characterized by Reed-Sternberg cells?

Answer 9

Hodgkin lymphoma

Question 10

What adult brain tumor found in the cerebral hemisphere that can cross the corpus callosum has pseudopalisading pleomorphic tumor cells?

Answer 10

Glioblastoma multiforme–Grade IV astrocytoma

Question 11

What disease causes “punched out” lesions in bone, which lead to fractures?

Answer 11

Multiple myeloma

Question 12

Multiple myeloma is a _______ cell cancer?

Answer 12

Plasma

Question 13

What is the most common mutation that occurs with CF and what does this cause a defect in?

Answer 13

deltaF508–leads to defective processing from the ER to the golgi

Question 14

What 2 tumor markers are often elevated with pancreatic cancer

Answer 14

CA 19-9 and carcinoembryonic antigen (CEA)

Question 15

What is the triad of Granulomatosis with polyangiitis?

Answer 15

Focal necrotizing vasculitis
Necrotizing granulomas in the lung and upper airway
Necrotizing GN

c-ANCA associated

Question 16

Which Thalassemia has increased HbF?

Answer 16

B-thalassemia major