MCQ Stuff Flashcards

(45 cards)

1
Q

What clotting factors are in the intrinsic pathway

A
  • Factor 12
  • Facto 11
  • Factor 9
  • Factor 8
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2
Q

What clotting factors require vitamin K

A
  • Factor 2 (prothrombin)
  • Factor 7
  • Factor 9
  • Factor 10
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3
Q

Thrombocytopenia

A

decreased platelets numbers

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4
Q

Hypercoagulability

A

increased tendency to clot

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5
Q

Hemophilia A –

A

genetic bleeding disorder associated with deficiency of clotting factor VIII

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6
Q

Haemophilia B

A

genetic bleeding disorder associated with deficiency of clotting factor IX

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7
Q

Polycythaemia

A

high number of red blood cells

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8
Q

Hypoxia

A

low level of oxygen in body tissue

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9
Q

Haemochromatosis

A

when body absorbs and stores too much iron from diet – results in oxidative stress

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10
Q

what bleeding disorders are defective production of Hb

A
  • Sickle cell anaemia
  • Thalassemia
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11
Q

What bleeding disorder is due to defective red blood cell

A
  • Spherocytosis
  • G-6-PD deficiency
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12
Q

What cranial nerves are from brachial arches

A

5,7,9,,10

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13
Q

What CN is from Brachial arch 1

A

CN V (V2, V3) - Trigeminal

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14
Q

What CN is from Brachial arch 2

A

CN VII - Facial

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15
Q

What CN is from Brachial arch 3

A

CN IX - Glossopharyngeal

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16
Q

What CN is from Brachial arch 4

A

CN X – Vagus

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17
Q

What CN is from Brachial arch 6

A

CN X – Vagus

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18
Q

What are the origins of the sympathetic system

A
  • Spinal cord segments T1-L2/L3
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19
Q

what are the origins of the parasympathetic system

A
  • Cranial Park: brainstem (CN 3,7,9,10)
  • Caudal part: Spinal cord segments S2-S4
20
Q

What does the ACA supply

A
  • Medial surface of the frontal and parietal lobes
  • Superior part of motor and sensory cortex (especially lower limb area)
  • Corpus callosum (anterior 4/5)
  • Parts of the cingulate gyrus
    Stroke – Leg weakness/sensory loss, personality change
21
Q

What does the MCA supply

A
  • Lateral surface of frontal, parietal, and temporal lobes
  • Primary motor and sensory cortex (especially face and upper limb areas)
  • Broca’s and Wernicke’s areas (dominant hemisphere)
  • Internal capsule, basal ganglia (via deep branches)
    Stroke – Face/arm weakness, aphasia or neglect
22
Q

What does the PCA supply

A
  • Occipital lobe (primary visual cortex)
  • Inferior temporal lobe
  • Thalamus, midbrain, posterior corpus callosum

Stroke – Visual field defects, sensory loss

23
Q

what is purulent exudate

A

a thick yellow fluid which contains dead neutrophils, bacteria, cell debris and protein rich fluid

24
Q

What is serious educate

A

a clear watery fluid which is low in cells and protein, is typically seen in early inflammation, blisters or mild injuries

25
what cells are APC
- Dendritic cells - Macrophage - B cell
26
What are examples of vasoactive mediators for inflammation
- Histamine - Bradykinin - Leukotrienes - C3a and C5a - Platelet activating factor - Prostaglandins
27
What are chemotactic mediators for inflammation
- Leukotrienes - C3a and C5a - Certain interleukins (IL-8) - Microbial components - Platelet activating factor
28
What is C-reactive protein
- Produced by the liver during acute phase of inflammation (in response to IL-6 and Il-8) - If there is high CRP then there is active inflammation - Albumin levels are decreased to priorities the making to C reactive protein in the liver
29
What is the function of C-reactive protein
- Enhancing phagocytosis – opsonization - Activation the complement system - Inflammation marker (releasing pro inflammatory cytokines)
30
What is COX-1
(Constitutive – meaning always present) – Produces prostaglandins that protect gastric mucosa, support renal blood flow and help in platelet aggregation via TXA2
31
What is COX-2
(is inducible) – Produces prostaglandins that promote pain, fever and inflammation and contribute to vascular permeability
32
What does TXA2 cause
- Vasoconstriction - Promotes platelet aggregation
33
what does central release of substance P, neurokinn A or CGRP cause
nociceptive transmission
34
what does peripheral release of substance P, neurokinn A or CGRP cause
neurogenic inflammation
35
What is perceptual detection
– ability to detect that a stimulus has occurred – will normally only happen when you get the summation of several receptor impulses
36
What is magnitude estimation
- How intense is the stimulus - Frequency coding
37
What is spatial discrimination
- Identifying the site or pattern of stimulation - Varies between body areas
38
What is feature abstraction
- Our ability to build up more complex patterns of sensation - Can combine a mixture of sensations – warm, soft, smooth ect to build more complex patterns of sensation
39
What is quality discrimination
- The ability to identify the different modalities of a particular sense e.g. with taste, sweet or salty
40
What is pattern recognition
- Our ability to recognise familiar patterns, novel patterns ect - For example, building up a picture from a series of dots or micro images
41
Amnesia def
loss of ability to recall one’s memories
42
Aphasia def
loss of ability to comprehend and express speech
43
Apraxia def
loss of ability to execute motor movements
44
Agnosia def
loss of ability to process sensory information (visual, auditory, tactile, or olfactory senses)
45
what does calbindin do
increases calcium binding protein in intestinal epithelial