Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Step 1 Clues > micro drill sheet part 3 > Flashcards

micro drill sheet part 3 Flashcards

(95 cards)

Start Studying
1
Q

WAS

A

Thrombocytopenia
IL-4, Eczema, 􏱶 IgM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

SCID

A

􏱷 Adenosine deaminase deficiency, T>B,
frameshift/nonsense mutation,
􏱸 bacterial & fungal infx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

CVID:Common variable immunodeficiency

A

Tyrosine kinase deficiency, late-onset, frameshift/
missense mutation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

HIV (HTLV-l)

A

Effects CD-4 rich tissues (brain, testicles,
cervix, rectum, blood vessels), T>B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Job Syndrome

A

red-headed female,
tyrosine kinase deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

B-cell def

A

􏰀 Bruton’s Agammaglobulinemia - Tyrosine kinase deficiency
􏰀 Leukemia
􏰀 Lymphomas
􏰀 See above for those with T-cell overlap

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

DiGeorge’s

A

T-cell
hypocalcemia,
problem with 3rd and 4th pharyngeal pouches,
deletion of chromosome 22
cardio facial malformation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

CD4 def

A

HIV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Chemical Uncouplers

A

􏰀 DNP
􏰀 Free Fatty Acids
􏰀 Aspirin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

ETC complex 1 poison

A

Sodium amytal, Rotenone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Complex 2 poison

A

Malonate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

complex 3 poison

A

Antimycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

complex 4

A

Cyanide
CO
chloramphenicol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

complex 5

A

Oligomycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Pyruvate
Amino acid

A

Gly, Ala, Ser

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Acetyl CoA

A

Phe, Iso, Thr, Tyr, Lys, Leu

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

alpha-KetoG

A

Glu, Gln

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Succinyl CoA

A

Phe, Ttp, Tyr

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Fumerate

A

Pro

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Asp, Asn

A

Oxaloacetate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

PKU def

A

Phenylalanine hydroxylase deficiency, needed to make tyrosine, leads to a lack of Dopamine, Epi and Norepi, melanin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Maple Syrup Urine Disease

A

􏱷 deficiency in branched amino acids (Iso, Leu, Val), defective transport in the kidneys

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Cystinuria

A

Cystathionine synthase deficiency;
cysteine, ornithine, lysine, and arginine; end up in urine, stones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

O-bonds aa

A

Ser, Thr, Trp

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
N-bond aa
Asp, Gln
25
acidic aa
Asp Glu
26
Basic aa
Arg Lys
27
Ketogenic Ketones KiLL
Lys, Leu
28
gluco-ketogenic
Phe Iso Thr Trp
29
Essential aa
PVT TIM HALL Phe def=Tyr essential Met def=Cys
30
Trypsin cuts right of
Arg Lys
31
Chymotrpsin cut right of
phe tyr trp
32
Elastase cuts right of
gly ser ala
33
mercaptoethanol cuts right of
Met cys
34
aminopeptidase cuts
amino terminal
35
carboxypeptidase cut left of
carboxy terminal
36
cyanobromid cut left of
met
37
cAMP
Sympathetic, catabolic, CRH
38
cGMP
Parasympathetic, anabolic
39
2nd msg for Smooth muscle contraction by horm/NT. All hypothalamic hormones (except CRH)
IP3/DAG
40
Smooth muscle contraction by distention
􏰀 Ca-Calmodulin
40
2nd msg 4 Insulin and all growth factors
Tyrosine Kinase
40
Nitrogen Oxide
Nitrates Viagra ANP LPS: lipopolysaccharide
40
co-factor for Dehydrogenase
TPP--------------- Thiamin (B1) 􏰀 Lipoic Acid. - B4 􏰀 CoA-------------Pantothenic Acid (B5) 􏰀 FAD------------- Riboflavin (B2) 􏰀 NAD------------Niacin (B3)
41
X-linked Recessive
Burton' s Agammaglobulinemia 􏰀 CGD (NADPH Oxidase deficiency) Duchene's Muscular Dystrophy 􏰀 Color Blindness 􏰀 Hemophilia 􏰀 G6PD 􏰀 Lesch-Nyhan 􏰀 Fabry's 􏰀 Hunter's
42
X-lined Dominant
􏰀 Rett Syndrome 􏰀 Vitamin D-resistant Rickets 􏰀 Pyruvate DH deficiency Pseudohypoparathyroidism
43
Nephrotic Patterns of Vasculitis inflammation and clot
􏰀 Renal Artery Stenosis -------Clot in front of renal artery 􏰀 Renal Failure -------- Clot off entire renal artery 􏰀 GN ------- Inflamed glomeruli
44
Nephrotic Patterns of Vasculitis inflammation and clot
􏰀 Papillary Necrosis -------- Clot in papilla 􏰀 Interstitial Nephritis ---------- Clot of medulla 􏰀 Focal Segmental GN ----------- Clot off pieces of nephron 􏰀 Rapidly Progressive GN --------- Clot off lots of nephrons
45
MC Nephrotic Disease in Adults
􏱷 Membranous GN
46
MC Renal Dz in Blacks/Hispanics
􏱷 Focal Segmental GN
47
MC Renal Disease in HIV/IVDA
􏱷 Focal Segmental GN
48
MC Renal Mass
􏱷 Cyst
49
MC Malignant Renal tumor in adults
Adenocarcinoma
50
MC Malignant Renal tumor in kids
􏱷 Wilm's tumor
51
MCC of Rapidly Progressive GN crescent Formations
􏱷 Goodpasture's
52
MC Nephrotic Disease in kids 2 weeks post URI
􏱷 Minimal Change Disease
53
Thrombolytic and Rescues tPA and streptokinase
Aminocaproic acid
54
Thrombolytic and Rescues warfarin
vit K
55
Thrombolytic and Rescues Heparin
protamine sulfate
56
Thrombolytic and Rescues if active hemorrhage
FFP
57
Pneumovax
Covers MC 23 strains 􏰀 Given at. 2,4 &6 months 􏰀 Given to anyone over 65 years old 􏰀 Anyone who is asplenic 􏰀 Anyone with end-organ damage (CF, RF, Nephrotic
58
Rashes Associated with Cancer urticaria (hives)
any, but especially lymphoma
59
Rashes Associated with Cancer Paget's dz
Intraductal carcinoma
60
Intraductal carcinoma seborrheic keratosis
Colon cancer (HIV is sudden 􏱸)
61
Rashes Associated with Cancer Actinic keratosis
Squamous cell carcinoma of skin
62
Rashes Associated with Cancer Dermatomyositis
Colon cancer
63
Rashes Associated with acanthuses nigracans
Visceral CA & end organ damage
64
Rashes Associated with erythema nodosum
Granulomatous (nonbacterial)
65
Ab SLE
Smith Double-stranded DNA Cardiolipin
66
Cardiolipin causes
activate vWF systemic clotting 3 4
67
Ab Drug Induced SLE
Histone
68
Progressive Systemic Sclerosis
Topoisomerase
69
Graves
TSH Receptor
70
CREST
Centromere
71
Goodpasture's
Type 4 Collagen
72
Primary Biliary Cirrhosis
Mitochondria
73
Alopecia Areata
Hair follicle
74
Rheumatoid Arthritis
IgG FC portion
75
Multiple Sclerosis
Myelin Receptors
76
Celiac Sprue
Gliaden/gluten
77
Type I Diabetes
Islet cell receptor
78
Vitiligo
Melanocyte
79
Myasthenia Gravis
Acetylcholine receptor
80
Mixed Connective Tissue Disease
Ribonuclear protein
81
Pernicious anemia
Intrinsic factor
82
Pemphigus vulgaris
Desmosome
83
Bullous pemphigoid
Hemidesmosome
84
Hashimoto's
Thyroglobulin Microsomal
85
Scleroderma
Smooth Muscle SCL-70
86
Sjogren's
Rho La
87
Wegener's
Proteinase c-ANCA
88
Polyarteritis Nodosa
p-ANCA
89
Idiopathic Thrombocytic Purpura
Glycoprotein IIb/IIIa
90
Cancer Grading
􏱷 Severity of microscopic change
91
Cancer Staging
􏱷 Degree of dissemination of tumor

Step 1 Clues (27 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions