Midterm I Final Review

Question 1

Type I Hypersensitivity

1. Type of Antibody Involved
2. Pathophysiology

Answer 1

1. IgE

2. Mast cell degeneration

Question 2

Type II Hypersensitivity

1. Type of Antibody Involved
2. Pathophysiology
3. Examples

Answer 2

1. IgM, IgG
2. antigen-antibody complex forms on cell surface
3. antibiotic allergies, thrombocytopenia, Hemolytic Disease of Newborn

Question 3

Type III Hypersensitivity

1. Type of Antibody Involved
2. Pathophysiology
3. Examples

Answer 3

1. IgM, IgG
2. antigen-antibody complex formed in circulation and then deposited
3. SLE (lupus), antibiotic allergy

Question 4

Type IV Hypersensitivity

1. Type of Antibody involved
2. Examples

Answer 4

1. T cell

2. Contact dermatitis, TB text, poison ivy, organ rejections, hashimoto’s thyroiditis

Question 5

Idiopathic vs Iatrogenic

Answer 5

• idio- unknown cause

- iatro- like nosocomial

Question 6

Phases of Healing

Answer 6

1. Inflammation (neutrophils and macrophages clean, blood clots scaffold)
2. Proliferation and New Tissue (collagen and growth factors)
3. Remodelling and Maturation (scar tissue formation and remodelling)

Question 7

Autoimmunity vs Alloimmunity

Answer 7

• auto- tolerance to self

- allo- transplant/graft

Question 8

Eosinophil

Answer 8

lysosome containing dissolves surface of membrane parasites

Question 9

Mast-Cell

Answer 9

contains histamine activates inflammatory response

Question 10

Hydrostatic Pressure vs Colloid-Osmotic Pressure

Answer 10

Hydrostatic- moves fluid out of vein

Colloid Osmotic- moves fluid into vein

Question 11

Secretions of Malignant Tumors

Answer 11

• ADH
• ACTH
• hypercalcemia
• pro-coagulation

Question 12

Cheyne Stokes vs Kussmaul

Answer 12

Cheyne-Stokes- successively larger deeper breaths, apnea

Kussmaul- rapid large breaths

Question 13

Status Asthmatics

Answer 13

• asthma that won’t respond to treatment