Class 4- Neurotransmitters Flashcards
1
Q
Describe Cholinergic Messengers
A
- ACh
- memory
2
Q
Describe Biogenic Amine Messengers
A
- Dopamine
- NE/E
- Serotonin
3
Q
Describe Amino Acid Messengers
A
- glutamate
- GABA (calming)
4
Q
Describe Neuropeptides
A
- endorphins and enkephalins
- somatostatin
- substance P
- melatonin
5
Q
Schizophrenia
A
- rare
- more prevalent in men
- 16-30yrs onset
6
Q
Etiology of Schizophrenia
A
- genetic
- stress events as “trigger”
- viral inx in utero
- chemical brain imbalance (glutamate, dopamine, GABA, serotonin)
- structural changes (atrophy of hippocampus, enlarged ventricles in brain)
7
Q
Positive Symptoms of Schizophrenia
A
- hallucinations
- delusions
- thought disorder
- movement disorder
- special language
8
Q
Negative Symptoms of Schizophrenia
A
- inability to express emotions
- hygiene
- no enjoyment
9
Q
Cognitive Symptoms of Schizophrenia
A
- attention
- memory
- planning
10
Q
Etiology of Major Depressive Disorder
A
- requires predisposition and trigger
- smaller hippocampus
- larger amygdala
- thyroid and adrenal effected
- decreased NE, serotonin, and dopamine
11
Q
Manifestations of Major Depressive Disorder
A
- decreased pleasure, mood, energy
- increased sleep
- decreased libido
- feelings of worthlessness and guilt
- decreased ability to concentrate and make decisions
- pain
- manifests as rage in men
12
Q
Bipolar Affective Disorder
A
- cyclical manic and depressive episodes
13
Q
Messengers affected by Bipolar Affective Disorder
A
- glutamate
- GABA
- Serotonin
- Dopamine
- NE
- Melatonin
14
Q
Parkinson’s
A
- dysfunction in substantia nigra and basal ganglia
- decreased dopamine secretion
