MODULE 5 PART 2.4: ACTIVATION AND RECEPTORS OF MACROPHAGES Flashcards
(6 cards)
1
Q
Macrophage can be greatly enhanced by what immunity ?
A
Innate immunnity
2
Q
Macrophages can be activated by ?
A
- TLRs such as LPS, CpG DNA
- Microbial carbohydrates
- Heat shock proteins
- Inflammatory products
3
Q
When monocytes first move into inflamed tissue, they produce the following effects :
A
- Increased amounts of lysosomal enzymes
- Increased phagocytic activity
- Increased expression of antibody and complement receptors
- Secrete more proteases
4
Q
The cytokines produced by inflammatory macrophages especially TNF-a and IL-12 activate ____ cells.
A
NK cells
5
Q
NK cells will secrete ____ that activates macrophages further.
A
interferon-y
6
Q
Macrophages also possess receptors for antibodies, complement components, and CD40. True or False?
A
True
