MODULE 7 PART 1: INTRODUCTION TO COMPLEMENT SYSTEM Flashcards
(11 cards)
A defense mechanism that can be activated by both innate and acquired immune mechanisms
Complement system
Consists of enzymatic pathways that cause specific proteins to bind covalently to the surface of invading microbes
Complement system
The complement system is activated by ?
- Antigen bodies attached to a surface of an organism
- Complex carbohydrates found on the surface of infectious agents
The proteins that form the complement system are labeled numerically with the prefix ___.
C1
What are the complement system components synthesized in liver?
- C3
- C6
- C8
- B
What are the complement system components synthesized in macrophages?
- C2
- C3
- C4
- C5
- B
- D
- P
- I
What are the complement system components synthesized largely in neutrophils?
- C6
- C7
What are the key complement system components in classical pathway?
- C1q
- C1r
- C1s
- C4
- C2
- C3
What are the key complement system components in alternative pathway?
- D
- B
What are they key complement system components in terminal classical pathway?
- C5
- C6
- C7
- C8
- C9
What are the control proteins in complement system?
- C1-INH
- C4BP
- H
- I
- Ana INH
- P
- S
