Movement disorders 2 Flashcards Preview

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Flashcards in Movement disorders 2 Deck (22)
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1
Q
Nature of movement in “Flapping Tremor” asterixis
A
1. Hold arms up with palms forward and tell patient to “stop”: see tics of hands.

2.Not frequent, seen mostly in young people
2
Q
“Flapping Tremor” asterixis: associated disease
A
Wilson’s Disease, liver failure, uremia / kidney failure (only Wilson’s results in copper problems, the others involve other toxins)
3
Q
cause of “Flapping Tremor” asterixis
A
Copper accumulation in the lentiform nucleus causing basal ganglia degeneration
4
Q
treatment for “Flapping Tremor” asterixis
A
chelating agents such as penicillamine
5
Q
nature of movement of tics
A
1. Brief, intermittent movements or sounds
2. Sudden, abrupt, transient
3. Repetitive, coordinated
4. Vary in intensity
5. Repeated at irregular intervals
6. May resemble gestures, normal behavior
7. Sometimes suppressible
8. May look like a voluntary movement
6
Q
associated diseases with tics
A
tourettes
7
Q
cause of tics
A
1. SLITRK1 Gene on chromosome 13 (one patient only)
2. AD in other cases
3. Otherwise idiopathic
8
Q
meds to treat tics
A
1. Clonidine (anti-HTN)
2. SSRIs (for OCD)
3. Neuroleptics
4. Tetrabenazine
5. Clonazepam
9
Q
chorea nature of movement
A
Irregular, brief, dancing-like, jerky movements

Move from one body part to another
10
Q
chorea associated disease
A
1. Huntington’s
2. Sydenham chorea (most common type of chorea in kids)
3. Chorea Gravidarum
4. Lupus: 3rd most common neurologic presentation of lupus
11
Q
causes of chorea
A
1. HD: CAG repeat
2. Sydenham: post streptococcal immune reaction
12
Q
dystonia nature of movement
A
Contraction of muscle agonists and antagonists

Sustained muscle contractions cause twisting, abnormal postures

Can be associated with tremor
13
Q
cause of primary dystonia
A
DYT 1-12
14
Q
cause of secondary dystonia
A
1. Neuro-degenerative disorders
2. Ischemic brain injury
3. Posttraumatic
4. Meds, toxins
15
Q
Tourette Syndrome is
A
Motor and vocal tics that are suppressible and last more than 1 year
16
Q
Tourette syndrome is associated with
A
ADHD, OCD, poor impulse control
17
Q
Tourette syndrome: motor
A
1. grimacing
2. blinking
3. nose twitching
4. lip pouting
5. hopping
6. clapping
7. touching
8. throwing
9. head banging
18
Q
Tourette Syndrome: vocal
A
1. fronts
2. throat clearing
3. barks
4. sniffling
5. shouting obscenities
6. utterations
19
Q
list hypokinesias
A
1. parkinson's
2. progressive supranuclear palsy
3. multiple systems atrophy
20
Q
Parkinson's disease signs
A
1. resting tremor
2. bradykinesia or akinesia
3. rigidity
4. non-motor symptoms: autonomic instability, sleep disturbances
21
Q
Progressive supranuclear palsy:
signs
A
1. impaired eye movements: can't look down
2. reptilian or scared look
3. falls within the first year
22
Q
Multiple systems atrophy: signs
A
1. Parkinsonism
2. cerebellar symptoms
3. gait ataxia
4. autonomic symptoms