Flashcards in Muscle Disease Deck (20)
What is the difference between polymyositis and dermatomyositis?
Dermatomyositis = polymyositis + skin changes
The risk of malignancy increases with polymyositis and dermatomyositis. True/False?
List the classic presenting MSK features of poly/dermato -myositis
Muscle weakness that worsens over months
Difficulty with daily tasks
List investigations for poly/dermato -myositis
Muscle enzyme (CK)
Which antibodies are associated with poly/dermato -myositis?
What is the definitive test for poly/dermato -myositis?
List the main treatment for poly/dermato -myositis
Immunosuppression (methotrexate, azathioprine)
What is the steroid usually used for poly/dermato -myositis?
Prednisolone 40mg daily
Inclusion body myositis is more common in males. True/False?
Is muscle weakness in inclusion body myositis usually symmetrical or asymmetrical?
CK levels in inclusion body myositis are increased to a lesser fold compared to poly/dermato -myositis. True/False?
Inclusion body myositis is associated with anti-Jo-1 antibody. True/False?
Polymyalgia rheumatica is associated with which arteritic disease?
Giant cell arteritis
Muscle weakness if a feature of polymyalgia rheumatica. True/False?
List the common features of polymyalgia rheumatica
Morning stiffness - can't get out of bed
What is the mainstay of treatment for polymyalgia rheumatica?
Low dose steroid - usually rapid/dramatic response
What is the commonest cause of chronic MSK pain?
Is fibromyalgia inflammatory?
Fibromyalgia is commoner in which sex?