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Flashcards in Immunology Deck (11):
1

Which HLA allele is susceptible in ankylosing spondylitis?

HLA B27

2

Which HLA allele is susceptible in SLE?

HLA-DR3

3

Which type of hypersensitivity reaction is involved in SLE?

Type III

4

Which diseases is anti-centromere antibody associated with?

CREST/limited scleroderma

5

Which diseases is anti-Jo-1 antibody associated with?

Polymyositis
Dermatomyositis
Interstitial lung disease

6

Which disease is anti-La antibody associated with?

Sjogren's syndrome

7

Which diseases is anti-ribonucleoprotein antibody associated with? (anti-RNP)

Mixed connective tissue disease
SLE

8

Which diseases is anti-Ro antibody associated with?

SLE
Sjogren's syndrome

9

Which disease is anti-Smith antibody associated with?

SLE (very specific)

10

Rheumatoid arthritis is an example of which type of hypersensitivity?

Type IV

11

What are the 2 main potent stimulators of joint damage in rheumatoid arthritis?

TNF
IL-1