Neurotransmitters Flashcards Preview

Physiology > Neurotransmitters > Flashcards

Flashcards in Neurotransmitters Deck (23)
Loading flashcards...
1
Q

The enzyme that creates acetylcholine

A

Choline Acetyl Transferase

2
Q

Decreased level of acetylcholine is associated with these diseases (dementia)

A
  1. Huntington’s dementia

2. Alzheimer’s dementia

3
Q

Norepinephrine is found in the ___ of pons

A

locus ceruleus

4
Q

___ is a neuroMODULATOR in the CNS while a neuroTRANSMITTER in the PNS

A

Norepinephrine

5
Q

____ is the primary NT from post-ganglionic sympathetic neurons

A

Norepinephrine

6
Q

____ has a greater beta-2 action thus it relieves the effects of bee sting by decreasing contraction of airway smooth muscles

A

Epinephrine

7
Q

Dopamine is secreted in ____ which is a part of the brain that fine-tunes movement

A

substantia nigra

8
Q

Dopamine in the hypothalamus ____ prolactin (inhibits, modulates)

A

inhibits

9
Q

This dopamine receptor inhibitsadenylate cyclase using Gi protein

A

D2 receptor

D1 receptor activates adenylate cyclase using Gs protein

10
Q

Nitric oxide can be derived from what amino acid?

A

Arginine

11
Q

Serotonin is derived from what amino acid?

A

Tryptophan

12
Q

Serotonin is found in the ____ of the brain stem

A

median raphe

13
Q

Low levels of the NT is associated with depression

A

Serotonin

14
Q

____ NT is a vasodilator and an inhibitory NT

A

NO

15
Q

This NT is the main inhibitory NT of the spinal cord

A

glycine

16
Q

This NT is the main inhibitory NT in the brain

A

GABA

GABAa decreases anxiety

17
Q

The main excitatory NT in the brain is ____ which is formed from the reactive amination of alpha ketoglutarate

A

Glutamate

18
Q

____ NT for acute, electric pain

A

Fast pain, glutamate

Slow pain - burning, aching, Substance P

19
Q

What are the phenylalanine derivatives?

A
Tyrosine, T3/T4
Melanine
L-Dopa
Dopamine
NE
Epi
20
Q

What are the tryptophan derivatives?

A

Melatonin
Serotonin
Niacin

21
Q

____ receptors refers to a group of cholinergic receptors linked to ion channels in the cell membrane

A

Nicotinic = always excitatory

Nico = ion

22
Q

___ receptors refer to a group GPCR (cholinergic) that phosphorylate second messenger

A

Muscarinic

M1,3,5 = excitatory
M2,4 = inhibitory
23
Q

Differentiate adrenergic vs cholinergic

A

Adrenergic = bind to noradrenaline and noradrenaline; always sympathetic = can either be alpha and beta receptors

Cholinergic = bind to acetylcholine; can either me nicotinic or muscarinic