NEW 3 Flashcards

1
Q

Amino acid sequence of protein is written…

A

in DNA

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2
Q

RNA has a series of…

A

NONoverlapping three base “words” called codons

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3
Q

Transcription rewrites the DNA —> RNA, substituting..

A

U for T
Uracil for Thymine

A + U in RNA**

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4
Q

Each amino acid is…

A

specified by codon

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5
Q

__ codons are possible

A

64

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6
Q

Some amino acids have more than…

A

one possible codon

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7
Q

Genetic code decides how codons are…

A

translated into amino acids

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8
Q

Three nucleotides specify ONE…

A

amino acid in the genetic code

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9
Q

61 codons correspond…

A

to amino acids

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10
Q

AUG

A
  • START of TRANSLATION

- codes for methionine

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11
Q

3 “stop” codons signal…

A

end of translation

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12
Q

Genetic Code

A

is universal, shared by organisms from simple to complex

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13
Q

RNA molecule is _______ from gene

A

transcribed

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14
Q

RNA polymerase

A

RNA nucleotides linked by transcription enzyme

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15
Q

Promoter

A

nucleotide sequence signal = “start transcribing”

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15
Q

Cap and tail of extra nucleotides are added to ends of the mRNA to…

A
  • help RNA leave nucleus
  • protect RNA from damaging enzymes
  • help RIBOSOMES bind to mRNA
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16
Q

INITIATION

A

RNA polymerase CONNECTS to promoter

17
Q

ELONGATION

A
  • amino acids added ONE by ONE

- RNA grows longer

18
Q

Removes introns and joins exons producing continuos coding sequence

A

RNA splicing

19
Q

TERMINATION

A
  • RNA polymerase reaches base in DNA template called TERMINATOR, signals the END of gene
  • polymerase detaches from RNA molecule and gene
20
Q

tRNA molecules

picks up _____ _____ and brings them to _______

A

amino acids

cytoplasm

21
Q

Translation - can be divided into same…

A

three phases as transcription:

1 ) initiation

2) elongation
3) termination

22
Q

Ribosomes are composed of…

A

ribosomal rRNAs and protein

23
Q

Ribosomes have binding sites for…

A

mRNA and tRNAs

24
Messenger RNA (mRNA)*
-encodes amino acid sequence
25
tRNA molecules use special...
TRIPLET of bases called anticodon
26
P site
first tRNA occupies the p site, which holds growing polypeptide chain
28
A site
available for next tRNA (transfer RNA)
28
Translation termination
- ribosome reaches STOP codon - completed polypeptide is released from the last tRNA - ribosome goes back into separate subunits
29
3 types of Mutations
1) base substitution 2) insertions 3) deletions
30
anticodon
- triplet bases | - complements codons in mRNA
31
Any change in nucleotide sequence of DNA
mutation
32
Base substitution
1) have NO effect, silent mutation 2) leads to IMPROVED protein that helps enhance survival 3) nonsense mutation
33
Mutations can involve large chromosomal regions or...
just single nucleotide pair
34
Mutations caused by...
random errors during DNA replication
35
Mutagens: cause _______
mutations | ex. high energy radiation, chemicals
37
Nonsense mutation
CHANGES amino acid into stop codon
38
Insertions & Deletion mutations
- alter reading frame - produce NONFUNCTIONAL polypeptide - change in amino acid sequence downstream of mutation
38
Codons are ____ to each other, NO gaps in between
next
39
mRNA contains INtrons...
interrupts sequences that separates exons