Ocular

Question 1

Antibiotics

Answer 1

Sulfacetamide, fluoroquinolones, macrolides, amino glycides, polymyxins

Question 2

Antifungal

Answer 2

Natamycin

Question 3

Antihistamine

Answer 3

Emedastine difumurate 0.05%, epinastine HCL 0.05%, alcaftadine 0.25%, Azelastine 0.05%, Ketotifin fumurate

Question 4

NSAIDs

Answer 4

Dicoflenac sodium, ketorolac tromethamine, Flurbiprofen sodium, bromfenac, bromfenac sodium, nepafenac

Question 5

Glaucoma

Answer 5

Prostaglandins, beta blockers, alpha agonists, carbonic anhydrase inhibitors, topical

Question 6

Macular degeneration

Answer 6

VEGF inhibitors

Question 7

VEGF inhibitors

Answer 7

Pepgaptanib, bevicizumib, aflibercept

Question 8

Cyclosporine Indications

Answer 8

Keratoconjunctivitis sicca

Question 9

Cyclosporine MOA

Answer 9

Immunosuppressant; specified for treatment of keratoconjuntivitis sicca due to inflammation

Question 10

Cyclosporine contraindications

Answer 10

Hypersensitivity, contact wearers

Question 11

Cyclosporine AR

Answer 11

Burning

Question 12

Pegaptanib indications

Answer 12

VEGF inhibitor for TX of macular degeneration

Question 13

Pegaptanib AR

Answer 13

Blepharitis, conjunctivitis, increased IOP, photopsia…

Question 14

Bevacizumab indications

Answer 14

Cancer, macular degeneration

Question 15

Bevacizumab AR

Answer 15

High risk of infection from repetitive use of vial

Question 16

Aflibercept indications

Answer 16

Macular degeneration

Question 17

Aflibercept AR

Answer 17

Conjunctival hemorrhage, pain, cataract, floaters, bit real detachment, increased IOP

Question 18

Lubricants

Answer 18

Cyclosporine, acetylcysteine

Question 19

Prostaglandins

Answer 19

Latanoprost, travoprost, tafluprost, unoprostone, bimatoprost

Question 20

Beta blockers

Answer 20

Timolol, levobunolol, carteolol, metipranolol, betaxolol

Question 21

Alpha agonists

Answer 21

Apraclonidine, brimonidine, brimonidine/timolol

Question 22

Beta blockers MOA

Answer 22

Decrease aqueous humor production 20-25%; beta-adrenergic antagonists

Question 23

Alpha agonist MOA

Answer 23

Increase aqueous outflow 20-25%

Question 24

Alpha agonist AR

Answer 24

Conjunctival injection, hyperemia, vision change, headache, fatigue

Question 25

Carbonic anhydrase inhibitors

Answer 25

Acetazolamide, dorzolamide, dorzolamide/timolol, brinzolamide

Question 26

Carbonic anhydrase inhibitors oral

Answer 26

Acetazolamide

Question 27

Carbonic anhydrase inhibitors MOA

Answer 27

Decreases aqueous humor secretion by decreasing bicarbonate formation 15-20%

Question 28

Cycloplegics

Answer 28

Anticholinergics. Dilate pupils by weakening ciliary muscles

Question 29

Cycloplegics indication

Answer 29

Ulcers, uveitis, cycloplegic refraction

Question 30

Mucolytic

Answer 30

Acetylcysteine

Question 31

Acetylcysteine MOA

Answer 31

Breaks up mucus

Question 32

Sulfacetamide 10% solution indication

Answer 32

Broad spectrum antibiotic. Treatment for bacterial conjunctivitis

Question 33

Sulfacetamide MOA

Answer 33

Inhibits nucleic acid synthesis. Bacteriostatic

Question 34

Sulfacetamide contraindications

Answer 34

Hypersensitivity

Question 35

Sulfacetamide drug interaction

Answer 35

Silver

Question 36

Fluoroquinolones

Answer 36

Besifloxacin, moxifloxacin, ofloxacin, levofloxacin .5 & 1.5, gatifloxacin, ciprofloxacin

Question 37

Fluoroquinolones indications

Answer 37

Broad spectrum antibiotic for Bacterial conjunctivitis

Question 38

Fluoroquinolones MOA

Answer 38

Inhibits DNA gyrase; bactericidal

Question 39

Fluoroquinolones contraindications

Answer 39

Hypersensitivity

Question 40

Fluoroquinolones AR

Answer 40

Burning, FBS, photophobia, blurred vision, tearing, dryness

Question 41

Macrolides

Answer 41

Ezithromycin, azithromycin

Question 42

Macrolides indications

Answer 42

Broad spectrum antibiotic for bacterial infections. Specificity for chlamydia and gonnorhea

Question 43

Macrolides MOA

Answer 43

Inhibits bacterial protein synthesis; bacteriostatic

Question 44

Macrolides contraindications

Answer 44

Hypersensitivity

Question 45

Macrolides AR

Answer 45

Irritation, redness, hypersensitivity

Question 46

Aminoglycides

Answer 46

Gentamicin, tobramycin, tobramycin/dexamethasone, tobramycin/fluorometholone

Question 47

Aminoglycides MOA

Answer 47

Binds ribosomal RNA disrupting translation. Bactericidal

Question 48

Aminoglycides indications

Answer 48

Broad spectrum antibiotic for ocular bacterial infections associated with inflammation

Question 49

Aminoglycides contraindications

Answer 49

Hypersensitivity, dexamethasone will make fungal infections worse

Question 50

Aminoglycides AR

Answer 50

Ulcers, irritation, conjunctivitis, thrombocytopenic purpura

Question 51

Polymyxins

Answer 51

Trimethoprim, bacitracin

Question 52

Natamycin indication

Answer 52

Antifungal

Question 53

Natamycin MOA

Answer 53

Alters fungi membrane permeability. Fungicidal

Question 54

Antihistamines

Answer 54

Emedastine difumurate, epinastine HCL, alcaftadine, Azelastine, Ketotifin fumurate

Question 55

Antihistamine MOA

Answer 55

H1 receptor antagonist

Question 56

NSAIDs

Answer 56

Dicloflenac sodium, ketorolac tromethamine, Flurbiprofen sodium, bromfenac, bromfenac sodium, nepafenac

Question 57

NSAID indications

Answer 57

Pain and inflammation post-op, corneal abrasion, blepharitis

Question 58

Bromfenac contraindications

Answer 58

Sulfite allergy

Question 59

NSAIDs AR

Answer 59

Delayed healing, keratitis, corneal melt, burning, lacrimation, FBS, increased IOP

Question 60

Prostaglandins indications

Answer 60

First line of TX in patients with increased IOP reduces IOP 20-25%

Question 61

Prostaglandin MOA

Answer 61

Increases aqueous humor outflow

Question 62

Prostaglandin AR

Answer 62

Hyperpigmentation, lash growth, uveitis, herpes virus activation