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Flashcards in Tetracyclines Deck (10):
1

Tetracyclines

Tetracycline, doxycycline, demeclocycline, minocycline, tigeclycline

2

MOA

inhibit protein synthesis by binding at the 30s ribosomal subunit. bacteriostatic

3

Spectrum

Broad spectrum

4

tetracycline Indications

URI, LRI, SSTI, rickettsia infections, malaria prophylaxis,

5

Doxycycline indications

acne and rosacea, lyme and vibrio, Anthrax

6

Tigecycline indications

complicated SSTI and intra-abd infections

7

ADR

Tooth discoloration, photosensitivity, NVD, Jarisch-herxheimer rxn

8

doxycycline ADR

black hairy tongue

9

Minocycline ADR

skin pigmentation (greyish)

10

demeclocycline indication

primarily for SIADH