Flashcards in Tetracyclines Deck (10):
1
Tetracyclines
Tetracycline, doxycycline, demeclocycline, minocycline, tigeclycline
2
MOA
inhibit protein synthesis by binding at the 30s ribosomal subunit. bacteriostatic
3
Spectrum
Broad spectrum
4
tetracycline Indications
URI, LRI, SSTI, rickettsia infections, malaria prophylaxis,
5
Doxycycline indications
acne and rosacea, lyme and vibrio, Anthrax
6
Tigecycline indications
complicated SSTI and intra-abd infections
7
ADR
Tooth discoloration, photosensitivity, NVD, Jarisch-herxheimer rxn
8
doxycycline ADR
black hairy tongue
9
Minocycline ADR
skin pigmentation (greyish)
10