Flashcards in Cephalosporins Deck (18):
1
MOA
inhibits bacteria cell wall synthesis
2
Spectrum
Staph, Strep, pneumococcus, E. coli, K. pneumo, P. mirabilis
3
1st generation
cephalexin, cefazoline, cefadroxil
4
1st generation indications
GAS pharyngitis, impetigo, SSTI, UTI
5
1st generation contraindications
PCN allergy
6
1st generations ADR
NVD, pancytopenia, hepatitis, CDAD
7
2nd generation
cefaclor, cefprozil, cefuroxime, ceftetan, cefoxitin, ceforoxime
8
2 Spectrum
extended gram -
9
2 indications
GAS pharyngitis, AOM, acute sinusitis, bronchitis, SSTI, UTI, early lyme, preop prophylaxis, bone/joint
10
3rd generation
cefixime, ceftibuten, cefpodoxime, cefditoren, ceftazidime, ceftriaxone, cefotaxime
11
3 spectrum
better gram -, some cross BBB, some active against pseudomonas
12
3 ADR
can be seizures
13
4th generation
cefepime
14
4 spectrum
broad-pseudomonas, strep, enterobacter
15
4th indications
pneumonia, febrile neutropenia, UTI, SSTI, peritonitis
16
5th generation
ceftaroline
17
5th indications
CAP, SSTI
18