Cephalosporins Flashcards Preview

Pharmacology > Cephalosporins > Flashcards

Flashcards in Cephalosporins Deck (18):
1

MOA

inhibits bacteria cell wall synthesis

2

Spectrum

Staph, Strep, pneumococcus, E. coli, K. pneumo, P. mirabilis

3

1st generation

cephalexin, cefazoline, cefadroxil

4

1st generation indications

GAS pharyngitis, impetigo, SSTI, UTI

5

1st generation contraindications

PCN allergy

6

1st generations ADR

NVD, pancytopenia, hepatitis, CDAD

7

2nd generation

cefaclor, cefprozil, cefuroxime, ceftetan, cefoxitin, ceforoxime

8

2 Spectrum

extended gram -

9

2 indications

GAS pharyngitis, AOM, acute sinusitis, bronchitis, SSTI, UTI, early lyme, preop prophylaxis, bone/joint

10

3rd generation

cefixime, ceftibuten, cefpodoxime, cefditoren, ceftazidime, ceftriaxone, cefotaxime

11

3 spectrum

better gram -, some cross BBB, some active against pseudomonas

12

3 ADR

can be seizures

13

4th generation

cefepime

14

4 spectrum

broad-pseudomonas, strep, enterobacter

15

4th indications

pneumonia, febrile neutropenia, UTI, SSTI, peritonitis

16

5th generation

ceftaroline

17

5th indications

CAP, SSTI

18

5th ADR

drug induced hemolytic anemia