Oxazolidinones Flashcards Preview

Pharmacology > Oxazolidinones > Flashcards

Flashcards in Oxazolidinones Deck (11):
1

Oxazolidinones

linezolid, Tidezolid

2

MOA

inhibits cell wall synthesis by binding at the 50s ribosomal subunit

3

Spectrum

activity against gram (+) staph, strep, enterococcus, anaerobic bacilli, cocci

4

indications

HAP, CAP, VRE, SSTI

5

ADR

NVD, pancytopenia, HA, lactic acidosis

6

Lipoglycopeptides

oritavancin, dalbavancin

7

Lipglycopeptides MOA

interferes with cross linking of peptidoglycan in bacterial cell walls

8

Lipoglycopeptides indications

acute bacterial skin and skin structure infections

9

Mupirocen

impetigo, intranasal MRSA colonization

10

Quinupristin-dalfopristin

serious or life threatening vancomycin resistant enterococcus infections, complicated SSTI

11

colistin

last line!