Oocytes and sperm Flashcards

(40 cards)

1
Q

What happens before birth with eggs?

A

start as oognoium which undergoes mitosis to form a primary oocyte which starts meoissi but arrests in its progress

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2
Q

What phase does the primary oocyte arrest in?

A

prophase 1

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3
Q

What happens during puberty to the egg?

A

meiosis occurs giving rise to a secondary oocyte and a polar body

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4
Q

What phase does the secondary oocyte arrest in?

A

metaphase 2

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5
Q

How is a polar body formed?

A

when the egg divides, it does so unequally, with the majority of cell material and organelles going into one cell (secondary oocyte) and the other set of chromosomes and a small amount of cytoplams forming a polar body

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6
Q

When would the secondary oocyte continue through meiosis II?

A

if it is fertilised in the uterus

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7
Q

Where does spermatogenesis occur?

A

in the wall of the seminiferous tubules

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8
Q

What are the sperm stem cells called?

A

spermatognoia

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9
Q

What happens when the spermatogonia undergoes mitosis?

A

one offsrping goes on to differentiate into a sperm cell whilst the other gives rise to the next generation of sperm

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10
Q

What is the cell formed at the end of meiosis called?

A

spermatid

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11
Q

When is a second polar body produced?

A

when the oocyte has completed meiosis

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12
Q

What are the two phases of the menstrual cycle?

A

follicular and luteal

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13
Q

What happens during the luteal phase?

A

development of the corpus luteum; induces preparation of reproductive tract for pregnancy

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14
Q

Where is gonadotrophin releasing hormone synthesised?

A

by neurons in the hypothalamus

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15
Q

Which hormones does GnRH stimulate the release of?

A

FSH and LH

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16
Q

What are the functions of FSH?

A

follicular development and thickens endometrium

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17
Q

What are the functions of LH?

A

peak stimulates ovulation; stimualtes corpus luteum development; thickens endometrium

18
Q

Where is oestrogen secreted?

A

primarily by the ovaries, byb adrenal cortex and by placenta in pregnancy

19
Q

What are the functions of oestrogen?

A

stimualtes thickening of endometrium; reponsible for fertile cervical mucus; maturations of ovarian follicles; mildly accelerates sodium and water reaborption by kidney tubules; increase water content of the uterus

20
Q

What happens when there is a high concentraion of oestrogen?

A

inhibits secretion of FSH and PRL; stimualtes ecretion of LH

21
Q

What happens when there is a low conc. of oestrogen?

A

stimulates secretion of PRL

22
Q

What are the functions of progesterone?

A

inhibits secreiont of LH; increases basal body temp; relaxes smooth muscles; infertile mucus; maintains thickness of endometrium and pregnancy

23
Q

Where is progesterone produces?

A

by corpus luteum and placenta

24
Q

What hormone stimualtes follicular growth?

25
What hormone is produced by the developing follicle?
oestrogen
26
What does the increase in serum oestrogen do?
suppresses secretion of FSH and increases secretion of LH
27
What is the function of the progesterone produced by the corpus luteum?
to thicken endometrium to prepare for implantation
28
What happens to the corpus luteum if fertilisation does not occur?
corpus luteum begins to regress and production of progesterone and oestrogen decreases
29
What happens during the menstrual phase?
corpus luteum degenerates; cessation of progesterone and oestrogen produced by corpus luteum which causes the endometrium to degenerate and menstruation to occur
30
What does in the drop in serum oestrogen adn progesterone cause?
stimulates production of FSH and the beginning of a new cycle
31
How long after LH surge does ovulation occur?
36 hours
32
What is the route of sperm?
testes- epipdidymis- vas deferens- ejaculatory duct- urethra
33
What cells does LH act on in the male?
Leydig cells
34
What is the function of LEydig cells?
regulate testosterone secretion
35
What cells does FSH act on?
Sertoli cells
36
What is the function of sertoli cells?
to enhance spermatogenesis- essential for spermatid remodelling
37
How does the negative feedback of testosterone work?
suppresses GnRH bursts; reduces sensitivity of LH-secreting cells to GnRH; LH inhibited more than FSH
38
What hormone do the sertoli cells produce which has negative feedback?
inhibin
39
How long does it take to produce a sperm?
around 72 days
40
What is the name of the tail on a sperm?
cilium