Page 17 Flashcards

1
Q

2016 MAGNIMS recommended modification:

A

Dissemination in space - >or= 3 periventricular lesions, add optic nerve as additional
location, make juxtacortical to cortical/juxtacortical Dissemination in time - no changes needed, nonenhancing black holes not useful in adults but may help distinguish MS from ADEM in children

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2
Q

Subependymal giant cell astrocytoma (SEGA) virtually always occurs in the setting of what disease?

A

tuberous sclerosis

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3
Q

What are the 3 inherited cancer syndromes that demonstrate an enhanced propensity to develop IDH-wild-type GBMs?

A

NF1, Li-Fraumeni, and Turcot syndrome

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4
Q

What brain structure is also called the hypophysis cerebri?

A

pineal gland

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5
Q

What is the rarest, most malignant of all intracranial GCTs?

A

primary intracranial choriocarcinoma

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6
Q

Imaging triad that is present in most anaplastic meningiomas

A

extracranial mass, osteolysis, mushrooming intracranial tumor

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6
Q

*What brain tumor commonly presents with foraminal / lateral extension into the CPA?

A

ependymoma

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7
Q

Most important site for CSF turnover

A

dura mater aka pachymeninx

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7
Q

Only established environemental risk factor for meningioma

A

radiation

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8
Q

Where do chondrosarcomas classically arise from?

A

petrooccipital fissure

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9
Q

What pathology causes a pupil-involving third nerve palsy?

A

PCoA aneurysm - located in close proximity to the cisternal segment of the nerve
(pupilloconstrictor fibers of the nerve are located peripherally along its superolateral aspect)

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10
Q

Which CN is especially vulnerable to injury during closed head trauma because of the long course of its cisternal segment and its proximity to the tentorium?

A

CN IV (symptom: torticollis/wry neck/head tilt)

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11
Q

What pathology causes a pupil-sparing third nerve palsy?

A

microvascular infarction of the core of the nerve

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11
Q

Which CN is vulnerable to apical petrocitis as well as increased ICP?

A

CN VI

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12
Q

CN VII exits through what foramen?

A

stylomastoid foramen

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13
Q

Which of the four nerves within the IAC is the most anterosuperior?

A

CN VII (“7 up, coke down” tapos sa likod iyong superior and inferior vestibular nerves)

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14
Q

Which of the four nerves within the IAC is the most anterosuperior?

A

CN VII (“7 up, coke down” tapos sa likod iyong superior and inferior vestibular nerves)

15
Q

Which is the only CN with segments that may exhibit some enhancement?

16
Q

Which of the segments of the INFRATEMPORAL facial nerve is not surrounded by a robust vascular plexus?

A

a robust vascular plexus?
labyrinthine segment (therefore, kung nag-enhance baka always abnormal?)

16
Q

Which of the infratemporal facial nerve branches is affected first in the invasion of malignant parotid tumors through the stylomastoid foramen?

A

chorda tympani (kasi most distal; taste anterior 2/3) -> stapedius nerve (hyperacusis) - > greater superficial petrosal nerve (parasympathetic lacrimal gland)

16
Q

What bony bar separates the superior and inferior vestibular nerves?

A

falciform (transverse) crest

16
Q

In the coronal plane of the jugular tubercle and basiocciput, what structure represents the “eagle’s head”?

A

jugular tubercle

17
Q

In the coronal plane of the jugular tubercle and basiocciput, what foramen/canal
lies superolateral to the “eagle’s head and beak”?

A

jugular foramen

17
Q

In the coronal plane of the jugular tubercle and basiocciput, what foramen/canal
lies under the “eagle’s head and beak” / at the “neck” between the “beak” above and “body” below?

A

hypoglossal canal

18
Which of the 3 CNs that exit through the jugular foramen lies in the pars nervosa (anterior part)?
(anterior part)? CN IX (CN X and XI lies in the pars vascularis/posterior part)
18
What are the 3 compartments involved in a 3-component trigeminal schwannoma?
Meckel cave, posterior fossa through the porus trigeminus, and masticator space through the foramen ovale
19
Osseous mets are relatively rare in children except in what malignancy?
Neuroblastoma
20
Upper normal limit of pituitary height
6 mm - prepubescent children 8 mm - men and postmenopausal women 10 mm - puberty and young menstruating 12-14 - pregnant and postpartum lactating
20
What is the rule of ninety in adamantinomatous craniopharyngiomas?
90% mixed cystic/solid, 90% calcified, and 90% enhance
21
The only one of the nonadenomatous tumors that can present as a purely intrasellar mass
pituicytoma
22
nd brain Obligatory hallmark of Joubert syndrome and JS-related disorders
molar tooth sign
22
F disorders Single most impt risk factor for developing new primary CNS neoplasms
radiation therapy
22
What is the typical topographical pattern or progression of normal myelination?
inferior to superior, central to peripheral, posterior to anterior (Is CP pa?)
23
Earliest manifestation of NF1
cafe-au-lait spots/macules
23
Virtually pathognomonic of NF1
plexiform neurofibromas
23
Differentiate NF1 and NF2 in terms of their associated neoplasms
NF1=astrocytomas, NF2=ependymomas and meningiomas
23
Major feature of NF2
schwannomas
24
Hallmark of type 2 VHL
adrenal pheochromocytoma
24
Second pathologic hallmark of NF2
multiple meningiomas
24
Classic clinical triad of tuberous sclerosis complex
facial lesions (adenomata sebaceum), seizures, mental retardation
25
Meaning of PHACE syndrome
Posterior fossa malformations, Hemangioma, Arterial cerebrovascular anomalies, Coarctation of aorta and cardiac defects, and Eye abnormalities (PHACES - Sternal clifting or supraumbilical raphe)
26
Normal order of suture closure
metopic > coronal > lambdoid > sagittal