Parasites - Blood Protozoa Flashcards
Plasmodium vivax info
splenic rupture
only infects reticulocytes - low parasitic burden
Shuffners dots
Plasmodium falciparum info
infects any stage of RBC most common most severe most deadly Maurers dots
Plasmodium ovale info
only infected reticulocytes - low burden
trophs with single chromatin dot - Shuffners dots, fimbriation
smaller than P vivax, elongated to oval shape
Plasmodium malariae info
infects mature RBC
trophs thicker than P falciparum - band formation during maturation
Ziemans stippling
Plasmodium knowlesi info
most commonly in macaques, rare human infection
Plasmodium species infectious stage
Mosquito takes a blood meal (injects sporozoites)
Release of sporozoites
Plasmodium species diagnostic stage
Immature trophozoite (ring stage)
Mature trophozoite
Schizont
Gametocytes
Babesia infectious stage
Sporozoites
Tick takes a blood meal (sporozoites introduced into host)
Babesia diagnostic stage
Sporozoites enter erythrocytes and undergo asexual replication (budding)
Babesia info
merozoite stage = Maltese cross (pathognomonic)
Trypanosoma brucei infectious stage
Tsetse fly takes a blood meal (injects metacyclic trypomastigote)
Trypanosoma brucei diagnostic stage
Circulating trypomastigotes in blood during acute phase - Usually undetectable in latent phase
Trypanosoma brucei info
elongated body with posterior flagellum
central nucleus with posterior kinetoplast
buffy coat smear best for diagnosis
Trypanosoma brucei symptoms
Gambain - neurologic deterioration (chronic)
Rhodesia - rapid onset leading to possible death (acute, rapid)
Winterbottoms sign
invasion of CNS
Trypanosoma brucei classification
African sleeping sickness
Blood protozoa - Hemoflagellate
