Flashcards in Peds 2 Deck (74)
neonate with alopecia and orange-colored, nodular skin? Tx?
tx = remove before adolescence, can undergo malignant degeneration
enzyme defect in PKU
Newborn with vomiting, athetosis, seizures, developmental delay/MR, fair hair and skin
When is breastfeeding CI? (7)
HgE-Ag + Hep B, HIV, herpes on nipple, chemo, Lithium, radioactive iodide
neonatal PKU and galactosemia
Enzyme defect in galactosemia
Newborn with FTT, bilateral cateracts, jaundice, hypoglycemia?
What are galactosemia babies at increased risk of?
E. coli infxns
Signs of concern in neonate w/ jaundice (4)
present on 1st day of life, Total Bili >12, Direct Bili >2, rise of >5/day
Inherited causes of direct hyperbilirubinemia (2)
Dubin Johnson (black liver)
Rotor Syndrome (milder form)
TE atresia a/w?
VACTERL (vertebral,anorectal atreisa, cardiac, TE, radial/renal, limb)
Choanal atresia a/w?
CHARGE (coloboma, haert defects, atresia (choanal), retarded growth, GU, ear)
mature lungs lecithin:sphingomyeline ratio
3 syndromes a/w omphalocele
Edwards, Patau, Beckwith-Weidemann
Neonate with umbilical hernia and macroglossia (big tongue)
Structural abnormality that leads to infantile volvulus
Normal rotation of gut during development
270 CCW around SMA
meausre 17,OH-Progesterone before and after ACTH bolus
Tx 21alpha-hydroxylase deficiency
hydrocortisone/fludrocortisone + aldosterone
Neonate with RDS, hypocalcemia, polycythemia, dx?
maternal gestational DM
Empiric Tx neonatal sepsis
amp + gent
Empiric treatment of infant meningitis
cefotaxime + amp
MCCs of newborn sepsis
GBS, Listeria, E. coli
Neonate w/ maculopapular rash on palm/soles, sniffles and periostitis
Neonate w/ hydrocephalus, intracranial calcifications and chorioretinitis? Tx?
Pyrimethamine (sulfadiazine + leucovorin)
Neonate w/ cataracts, deafness, heart defects and extramedullary hematopoeisis
neonate w/ microcephaly, periventricular calcification, deafness, thrombocytopenia, petechia, seizures? Tx?
Tx = Ganciclovir
Neonate w/ limb hypoplasia, cutaneous scars, catacts, chorioretinitis, cortical atrophy
CONGENITAL varicella (not neonatal)
When and how do you treat NEONATAL varicella
if mom was exposed either 5 days prior or 2 days after delivery, give baby VZIG
Tx gonococcal conjunctivitis
IV cefotaxime or cefalexin