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Flashcards in Set 3 Deck (50)
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1

Ash leaf spots, cardiac and kidney tumors, seizures / developmental delay?

Tuberous Sclerosis (mutation in 2 tumor suppressor genes)

2

Lens dissociaton associated with (2)

homocysteinuria = downward
Marfan's = upward

3

AMS, ataxia, nystagmus and conjugate gaze palsy

Wernicke's encephalopathy (B1 thiamine def)

4

Pathogenesis of statin-induced myopathy

inhibits intracellular coenzyme Q10 synthesis

5

Pathogenesis of RHF in COPD patient

pulmonary HTN from chronic hypoxemia --> constriction of pulmonary arterial system

6

What do prolonged QRS vs. prolonged QT indicate?

QRS = bradyarrhythmia (BBB)
QT = tachyarrhythmia (subtype of Vtach)

7

Tx Dressler's Syndrome

NSAIDs > > corticosteroids

8

Banana bag

Thiamine 1st then dextrose, naloxone and O2

9

2 causes of pulsus paradoxus

I.e. drop in SBP >10 during Inspiration
1. Cardiac tamponade
2. Severe asthma/COPD
(during inspiration blood pools in the lungs --> decreased LV preload --> decreased CO)

10

Complications of Strep Pharyngitis vs. Impetigo?

Strep pharyngitis can lead to PSGN, rheumatic fever, scarlet fever
Impetigo can only cause PSGN

11

ST depression V1 and V2

Posterior wall MI

12

Dx, Tx heat stroke

T >105F
Tx evaporative cooling (water spray / fans)

13

Tx Raynauds

Nifedipine (dihydropyridine CCB)

14

2 major causes of pseudotumor cerebri?

Vit. A toxicity (isotretinoin or prolonged tetracylcine use), OCPs

15

Tx depression WITH insomnia

Trazadone

16

Exudative (increased protein) effusion withOUT evidence of infection

Malignancy --> BCA or Lung MC

17

2 cardiac problems where Mg sulfate is the Tx

Torsades and digoxin OD

18

Pathogenesis of hyperprolactinemia

decreased DA in hypothalamus/tuberoinfundibular pathway --> LOSS of normal inhibition on PRL release from ANTERIOR pituitary. Hence, see increased PRL in patients on antipsychotics (DA antagonists)

19

Immune response elicited by Pneumoccocal polyvalent (subunit) vaccine

B cell only b/c polysaccharides* can't be presented to T cells (peptides and proteins can be though)

20

Decreased grip --> nerve injured

ulnar --> INTEROSSEOUS muscles

21

Tx asystole or PEA

CPR --> epinephrine
DO NOT SHOCK unless in vfib or pulseless vtach

22

HTN, hematuria and abd mass in a young person, think? associated with? (2)

PKD (autosomal dominant)
a/w cerebral aneurysms and strokes

23

3 DA pathways and ass. conditions

mesolimbic - excitatory - schizophrenia (incr. DA)
tuberoinfundibular - inhibitory - hyperPRL (decr. DA)
nigrostriatal - inhibitory - parkinsonism (decr. DA)

24

JVD, Kussmaul's sign, hypotension, clear lung fields and NORMAL heart sounds (not muffled)? Tx?

RHF (vs. cardiac tamponade w/ muffled heart sounds).
Tx = IVF to sustain preload and BP, avoid nitro or diuretics

25

What is injured with fx of supracondylar region of humerus?

median nerve and/or brachial artery

26

Child with syncope and hearing impairment? Tx?

QT prolongation syndrome - often + FHx
Tx BB +/- pacemaker if sx

27

Tx DCM

BB or CCB

28

decreased radial pulses that disappear with deep inspiration?

pulsu paradoxus --> cardiac tamponade

29

RF for AAA, oeprative criteria

RF = age >60, SMOKING, fhx, atherosclerosis
(****NOT HTN which is RF for aortic dissection)
Operate if >5.5cm, symptomatic or rapidly expanding

30

Tx duration of lithium for bipolar disorder

1x = 1yr
3+ x = for LIFE