Pre-Existing Conditions in Pregnancy Flashcards Preview

Y3 Reproductive > Pre-Existing Conditions in Pregnancy > Flashcards

Flashcards in Pre-Existing Conditions in Pregnancy Deck (32)
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1

Name 3 antihypertensives that are safe in pregnancy

Labetalol, methyldopa, nifedipine

2

Which class of diabetic medications is unsafe in pregnancy, and what is the alternative?

Sulfonylureas
Switch to insulin

3

Chronic HTN increases the risk of what cause of postpartum bleeding?

Placental abruption

4

Does pregnancy increase MI risk?

Yes (3-4X increased)

5

Which 2 common antiepileptic drugs are unsafe in pregnancy?

Valproate and phenytoin

6

What is the management of an intrapartum seizure in a patient with no history of epilepsy?

Mg sulfate

7

What is the 1st line Mx of an intrapartum seizure in an epileptic PTx?

IV/PR/buccal benzo

8

What drugs should obese pregnant women be given as prophylaxis in pregnancy? And what for?

LDA against PET
LMWH against VTE

(double check that LMWH is the VTE prophylaxis)

9

What is the pathology of APS?

Connective tissue disease, acquired thrombophilia

10

Is a miscarriage of a morphologically normal or abnormal fetus more suspicious of APS?

Morphologically normal

11

What investigations are done for APS?

Anti-cardiolipin Ab, lupus anticoagulant

(2X 6wk apart)

12

When should you suspect a PTx has APS?

3+ miscarriages before 10wk
OR
1+ loss >10wk of morphologically normal fetus
OR
1+ preterm birth due to PET

13

What is the Mx of APS in pregnancy?

LDA + monitor

(If PMH miscarriage/PET add LMWH)

14

Where is the most common location of DVTs in pregnancy? And which leg is most commonly affected?

Ileo-femoral
Left leg

15

What two factors during pregnancy increase the risk of DVTs?

Hypercoaguable
Venous stasis

16

DVTs cause a raised WCC. T or F

True

17

What test is diagnostic of DVTS in pregnancy?

US
(Don't do d-dimers)

18

What imaging modality is used to see iliac thrombosis?

MRI

19

What is the DVT prophylaxis drug in pregnancy?

LMWH dalteparin

20

What is the Mx of DVT in pregnancy?

LMWH dalteparin + postnatal warfarin for 6 weeks
DOUBLE CHECK THIS

21

What Ix provides a definitive Dx in a suspected PE in pregnancies?

CTPA or VQ scan

22

What effect does pregnancy have on GFR?

Raised
(Hence increased drug elimination)

23

Most drugs cross the placenta. T or F

True
(Except those with large molecular weights)

24

Heparin crosses the placenta. T or F

False (large molecular weight)

25

Is warfarin safe in the 1st trimester? If no, why not?

Teratogen

26

Is warfarin safe in the 3rd trimester? If no, why not?

Increases risk of APH / PPH

27

Is warfarin safe in breastfeeding?

Yes

28

Are ACEIs safe in pregnancy?

No

29

Are ARBs safe in pregnancy?

No

30

Are statins safe in pregnancy?

No