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Flashcards in Assisted Conception, Ethics & TOP Deck (52)
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1

How many couple in the UK have fertility problem?

1 in 6
(half of these receive some form of Tx)

2

Name 5 methods of assisted conception

IVF
Intra-uterine insemination
ICSI
Donor insemination
Surrogacy

3

How long must a couple have been 'trying' to qualify for ACT?

2 years

4

What BMI range must both partners be in to qualify for ACT?

18.5-30

5

What are the lifestyle components of the criteria for ACT?

Neither partner smokes for pre 3 months + during ACT
Females must drunk <4 units / wk
Abstain drugs 1 yr

6

If 1 partner has a biological kid, can a couple still qualify for ACT?

Yes

7

If 1 partner has been sterilised in the past, can a couple still qualify for ACT?

No

8

What infections must you screen for in the assessment for ACT?

HIV
HCV
HBV
Rubella immunity

9

When must you take folic acid for ACT?

Pre 12 wk
+
1st 12wk

10

How many cycles of ACT can a couple receive on the NHS?

3

11

Method of intrauterine insemination:
prepared ______ inserted into _______ at time of ______

Method of intrauterine insemination:
prepared SEMEN inserted into UTERINE CAVITY at time of OVULATION

12

What is the success rate of IVF?

35%

13

What is the success rate of ICSI?

35%

14

Method of IVF:
1. give woman synthetic ____ and perform _____ on male.
2. ___ hours before oocyte recovery inject ____.
3. Collect ____ in theatre.
4. Incubate ____ at ___ degrees in culture medium.
5. Transfer _____ on day ____ or cryopreservation.

Method of IVF:
1. give woman synthetic GnRN and perform SPERM ANALYSIS on male.
2. 36 hours before oocyte recovery inject HCG.
3. Collect EGGS in theatre.
4. Incubate EGGS at 37 degrees in culture medium.
5. Transfer BLASTOCYST on day 5 or cryopreservation.

15

What is test in semen analysis?

Vol
No.
Motility
Progression

16

On what day after insertion should you perform a pregnancy test in IVF?

Day 16

17

How is azoospermia classified?

Obstructive and non-obstructive

18

What procedure is indicated in obstructive azoospermia?

Surgical sperm aspiration from testis

19

What procedure is indicated in non-obstructive azoospermia?

Surgical sperm aspiration from epididymis

20

In donor insemination, at what time is the semen inserted into the uterus?

Time of ovulation

21

What conditions of pregnancy are more common in assisted conception?

Ectopic pregnancy
Multiple pregnancy
Ovarian hyper-stimulation synd
Misscarriage

22

What is done to prevent ovarian hyper-stimulation synd in ACT?

Single embryo transfer at a cycle

23

What is the management of ovarian hyper-stimulation synd?

Fluids (thrombosis prophylaxis)
TED stocking
Fragmin

24

Does a fetus have legal rights?

No

25

Is sex selection in assisted conception legal?

Illegal unless serious medical condition related to gender

26

Is an embryo with 2 genetic mothers legal?

Only approved to Tx serious mitochondrial diseases

27

Is embryo research legal in the UK?

Yes, up to 14 days (when primitive streak appears)

28

Is preimplantation tissue typing legal in the UK?

Only for stem cell Tx of sibling w serious/life-threatening condition

29

What guidelines are used to asses capacity to consent in under 16 year olds?

Fraser guidelines
Guilick competence

30

At what age should you always report underage sex?

Under 13 years