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Flashcards in HIV Deck (57)
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1

Where in the world is HIV infection most common?

Sub-Saharan Africa

2

What type of virus is HIV?

Retrovirus

3

Why is HIV more common in MSM?

Rectal epithelium is thinner and largely non-keratinized so more easily penetrated by viruses
(hence anoreceptive sex as highest risk)

4

Name 4 modes of HIV transmission

Sex
PWID
Infected blood product
Mother-child

5

What enzyme is responsible for retroviruses unloading RNA into a host cell?

Reverse transcriptase

6

What types of organisms are the most common sources of infection in HIV?

Fungi
Viruses
Mycobacteria

7

When is the window period of HIV infection where infection is undetectable?

0-4wk (double check this)

8

What component of the immune system is found at lower levels in HIV?

CD4+

9

What component of the immune system is found at higher levels in HIV?

CD8+

10

There is a chronic state of immune activation in HIV infection. T or F

True

11

CD4 is a receptor protein, what type of immune cells is it present on?

T helper cells
Dendritic cells
Macrophages
Microglia

12

What are the stages of HIV infection?

Primary infection
Acute HIV syndrome
Asymptomatic phase
Constitutional phase
AIDS

13

Can you transmit HIV during the asymptomatic phase?

Yes

14

Is the virus active during the asymptomatic phase of HIV infection?

Yes, viral replication continues

15

How long post contact does primary HIV infection occur?

2-4wk

16

How does primary HIV infection present?

Fever
Maculopapular rash
Myalgia
Pharyngitis
HA
Aseptic meningitis

17

Give examples of opportunistic parasitic infections that occur in HIV/AIDS

Toxoplasmosis

18

Give examples of mycobacterium infections that occur in HIV/AIDS

TB
PCP

19

Give example of viral infections that occur in HIV/AIDS

HPV
CMV
HZ
HSV

20

What infection in HIV/AIDS presents with insidious SOB, a dry cough at exercise desaturation?

PCP pneumonia

21

What is the management of PCP pneumonia in HIV/AIDS?

Co-trimox

22

TB in HIV aids is [more/less] likely to be extra-pulmonary or miliary and is [more/less] likely to be drug resistant

More
More

23

What infection in HIV/AIDS causes multiple brain abscesses, chorioretinitis, seizures and fever?

Toxoplasmosis

24

What infection in HIV/AIDS causes retinitis, esophagitis, colitis - which presents as decreased visual acuity, floaters, abdo pain and PR bleeding?

CMV

25

What form of eczema is much more common in AIDS?

Seborrheic dermatitis

26

What is the infecting agent in progressive multifocal leukoencephalopy?

JC virus

27

How does HIV related cognitive impairment present?

Decreased short term memory

28

What derm condition flares up in HIV/AIDS?

Psoriasis

29

What type of malignancy can HSV cause in AIDS?

Kaposi's sarcoma

30

Where do Kaposi's sarcomas occur?

Skin
Mucosa
Lung
GI