PRE LECTURE 11-16 Flashcards Preview

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Flashcards in PRE LECTURE 11-16 Deck (61):
1

white blood cells (granulocytes, monocytes, and lymphocytes) are formed in the bone marrow

true

2

the lifespan of white blood cells is relatively long, so constant renewal is not necessary to maintain normal blood levels

false; short

3

in neutropenia, all of the cell lines are affected, resulting in anemia, thrombocytopenia, and agranulocytosis

false

4

infectious mononucleosis is a self-limiting disorder caused by the epstein-barr virus

true

5

non-hodgkin lymphoma is a form of lymphoma that is associated with the presence of an abnormal cell called a reed-sternberg cell

false; hodgkin lymphoma

6

common in chronic lymphocytic leukemia, especially in persons with advanced disease

colonial malignancy of B lymphocytes

7

more children are stricken with WHAT than any other form of cancer, and it is the leading cause of death in children between the ages of 1 and 14 years

ALL; acute lymphocytic leukemia

8

have a sudden and stormy onset with symptoms of depressed bone marrow function (anemia, fatigue, bleeding, and infections)

acute leukemias

9

leukemia’s are classified according to their predominant

cell type

10

chronic myelogenous leukemia is associated with the presence of WHAT, arising from a reciprocal translocation between the long arm of chromosome 22 and the long arm of chromosome 9

philadelphia chromosome

11

platelets are also known as leukocytes

false; thrombocytes

12

idiopathic thrombocytopenic purpura is an autoimmune disorder that affects the normal function and formation of platelets

false; results in platelet antibody formation and destruction of platelets

13

disseminated intravascular coagulation is a condition that results in simultaneous clotting and bleeding

true

14

the use of aspirin and other non steroidal anti-inflammatory drugs (NSAIDs) has been identified as a cause of impaired platelet function

true

15

most of the coagulation factors are proteins synthesized in the spleen

false; liver

16

orderly, stepwise process for stopping bleeding that involves vasospasm, formation of a platelet plug, and the development of a fibrin clot

hemostasis

17

a decrease in the number of circulating platelets is known as

thrombocytopenia

18

hemophilia a is an x- linked recessive disorder that involves a deficiency of factor

VIII

19

used to describe elevations in the platelet count above 1,000,000

thrombocytosis

20

fat soluble vitamin that is continuously being synthesized by intestinal bacteria, is necessary for normal activity of factors VII, IX, and X and prothrombin

vitamin k

21

there are two major types of hemoglobin; adult hemoglobin (HbA) and fetal hemoglobin (HbF)

true

22

sickle cell disease is a chronic disorder that results from changes in the shape, rather than the size of rbc cells

true

23

iron deficiency anemia only affects infants and toddlers

false ; all ages

24

the rate at which hemoglobin is synthesized depends on the availability of iron for heme synthesis

true

25

thalassemias are inherited disorders of platelet synthesis that cause severe bruising and bleeding

false

26

mature rbc

erythrocytes

27

the function of rbc is to transport ANSWER from the lungs to the tissues

oxygen

28

if rbc destruction is excessive, bilirubin production is increased, causing a yellow discoloration of the skin

jaundice

29

Rh disease of the newborn is an example of

acquired hemolytic anemia

30

a primary condition of bone marrow stem cells that results in reduction of all three hematopoietic cell lines; red blood cells, white blood cells, and platelets

aplastic anemia

31

creutzfeldt-jacob disease and mad cow disease are examples of prion-associated diseases

true

32

viruses are capable of replicating outside of a living cell

false ; incapable

33

term portal of entry refers to the process by which a pathogen enters the body

true

34

some fungi are components of normal human micro flora

true

35

all organisms have the potential to cause infectious illness in humans

true

36

infections that develop in patients while they are hospitalized

nosocomial hospital acquired infection

37

adding the suffix ANSWER to the name of the involves tissue usually designates inflammation of an anatomic location

-itis

38

the period during which the host experiences the maximum impact of the infectious process

acute stage of disease

39

refers to the particular collection of signs and symptoms expressed by the host during the disease course

symptomatology

40

ticks, mosquitoes, mites, and lice are examples of what

parasites/ arthropods

41

organisms that derive benefits from their biological relationship with another organism

parasites/ arthropods

42

active immunity is acquired through immunization or actually having the disease

true

43

t lymphocytes are responsible for humoral immunity

false; cell mediated

44

adaptive immunity / acquired immunity refers to immunity that is acquired through previous exposure to infectious and other foreign agents

true

45

thyroid gland plays a central role in the immune response

false; thymus gland

46

passive immunity represents a type of immunity that is transferred from another source, such as in uterus transfer of antibodies from mother to infant

true

47

consists of cellular and biochemical defenses that are in place before infection and respond rapidly to it

innate immunity/ native immunity

48

5 classes each with different role in the immune defense strategy

immunoglobulin

49

a large secondary lymphoid organ located high in the left abdominal cavity, filters antigens from the blood and is important in the response to systemic infections

spleen

50

substances that are foreign to the host and can stimulate an immune response

antigens

51

class of immunoglobulin that is involved in allergic and hypersensitivity reactions

IgE

52

allergic rhinitis is a systemic, life-threatening hypersensitivity reaction

false

53

virtually any food can product an atopic or nonatopic allergy

true

54

in graft versus host disease, the immune cells of the transplant recipient attack the donor cells of the transplanted organ

false

55

severe combined immunodeficiency is a disorder that results from the loss of b-cell function as well as t cell function

true

56

an hiv-infection person can only transmit the virus when symptoms are present and the antibody test is positive

false ; always can be transmitted

57

reactions are IgE-mediated reactions that begin rapidly often within minutes of an antigen challenge

type 1 hypersensitivity

58

a test in which purified protein derivative is injected under the skin, is an example of a delayed-type hypersensitivity

the tuberculin test

59

rheumatoid arthritis type 1 diabetes mellitus, ulcerative colitis, and myasthenia gravis are all examples of probable

type i hypersensitivity disease

60

hiv infected person is at risk for many ANSWER, potentially affecting the respiratory tract, the gastrointestinal tract, and the nervous system

opportunistic infections

61

refers to the inability to mount an immune response against a persons own antigens

self tolerance