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Flashcards in Principles of CNS Pharmacology Deck (23):
0

Percentage of the body's energy supply that the brain consumes

About 20%

1

The function of neurons

Process information

2

The gap between neurons that allows transmission from one neuron to another

synapse

3

Neuron type that responds to a stimulus

sensory neuron

4

Neuron type that elicits a response

Motor neuron

5

Neuron type that integrates signals and makes connections with other neurons

Interneurons

6

Portion of neurons that forms grey matter

cell bodies

7

Multiple fine processes that extend from the cell body and recieve synaptic contacts from other neurons

dendrites

8

One process that extends from the cell body and sends info to other neurons

Axon

9

Portions of neurons that make up white matter

Axons

10

The highly specialized anatomical feature designed specifically to allow neurons to transmit info to other neurons

Presynaptic terminal

11

Ion that is relatively permeable through the neuron cell membrane and has a higher concentration inside the cell than outside

K+

12

The trigger zone of the neuron where integrations occur

Axon hillock

13

A brief all or none depolarization and repolarization of the membrane potential due to the activation of voltage sensitive Na+ channels

action potential

14

When several excitatory postsynaptic potentials arrive at the axon hillock simultaneously

Spatial summation

15

When post synaptic potentials created at the same synapse in rapid succession can be summed

Temporal summation

16

Small organelles that store neurotransmitters

synaptic vesicles

17

The major excitatory neurontransmitter in the brain

Glutamate

18

Inotropic glutamate receptor that is only permeable to Na+ and responds at normal resting potential

AMPA receptors

19

Inotropic glutamate receptors that are permeable to Na+ and Ca2+ and respond at depolarized potentials

NMDA receptors

20

What blocks NMDA receptors from opening at normal resting potential

MG2+

21

Pharmacologic agents that promote the conversion of plasminogen to plasmin

Thrombolytic agents

22

The key structural protein in most blood clots

Fibrin