Pulmonary Therapeutics Flashcards
(20 cards)
A plug in the mainstem bronchus that obstructs airflow with collapse of affected lung tissue
atelectasis
The filling of alveoli with fluid or blood cells
consolidation
Chest condition characterized by a disturbance in ventilation due to decreased chest wall or lung movement
Restrictive
3 main symptoms associated with asthma
dyspnea
wheezing
cough
% improvement during the pre/post-bronchodilator challenge that represents reversible airway obstruction
> 12%
Normal FEV1/FVC ratio
> 75%
Normal FEV1
> 80%
Normal FVC
> 80%
FEV1/FVC ratio that normally represents restrictive lung disease
> 88%
FEV1/FVC ratio that normally represents obstructive lung disease
% of predicted DLco that is considered abnormal
The protein responsible for the hydolysis of membrane phospholipids, releasing arachidonic acid
Phospholipase A2
3 cysteinyl leukotrienes
LTC4, LTD4 and LTE4
Enzyme that catalyzes arachidonic acid to cysteinyl leukotrienes
lipoxgenase
An antiprotease deficiency that leads to risk of COPD
alpha-1 antitrypsin deficiency
A chronic productive cough for 3 months during 2 consecutive years
Chronic bronchitis
Typical presenting symptom in emphysema
dyspnea
Typical presenting symptom in chronic bronchitis
cough
Type of emphysema likely to get pulmonary HTN
chronic bronchitis
Chest condition characterized by a disturbance in ventilation due increased resistance to airflow in the airways
Obstructive