Pulm #5 Flashcards

(48 cards)

1
Q

What is a pneumothorax?

A

-Air in the pleural space leading to collapse of the lung from positive intrapleural air pressure

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2
Q

What is a primary spontaneous pneumothorax vs a secondary spontaneous pneumothorax?

A
  • Primary: atraumatic and no underlying lung disease. Tall, thin men who are smokers
  • Secondary: underlying lung disease
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3
Q

A tension pneumothorax is any type in which

A

positive air pressure pushes the trachea, great vessels, and heart to the contralateral side

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4
Q

Symptoms and physical exam findings of a pneumothorax

A
  • Chest pain, unilateral and pleuritic. Sudden, dyspnea
  • Hyperresonance to percussion, decreased fremitus, and decreased breath sounds
  • Tension: Increased JVP, systemic hypotension, pulsus paradoxus
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5
Q

Initial diagnostic for a pneumothorax

A
  • Chest radiograph (expiratory upright view)
  • -Companion lines: visceral pleura line running parallel with ribs
  • -Decreased peripheral markings
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6
Q

Treatment for small PSP < 3 cm from chest wall at apex

A

Observation and supplemental oxygen

  • May be discharged if stable and repeat films after 6 hours excludes progression
  • Chest tube thoracotomy is worse on repeat films
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7
Q

Treatment for large PSP ( > 3 cm from chest wall at the apex)

A

Needle or catheter aspiration vs chest tube or chest thoracotomy

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8
Q

If the pneumothorax is a stable secondary spontaneous type, what is the treatment?

A

Chest tube or catheter thoracotomy + hospitalization

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9
Q

If the pneumothorax is a tension type from a car accident, during CPR, or PEEP ventilation, what is the treatment?

A

-Needle aspiration followed by chest tube thoracostamy

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10
Q

Patient education if they have a pneumothorax?

A

-Avoid pressure changes for 2 weeks (high altitudes, smoking, unpressurized aircrafts, scuba diving)

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11
Q

What is pulmonary hypertension defined as?

A

Elevated mean pulmonary arterial pressure > 20 mmHg with a pulmonary vascular resistance > 3 Wood units

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12
Q

What is the pathophysiology of pulmonary hypertension?

A

Increased pulmonary vascular resistance leads to RVH, increased RV pressure and eventually right sided heart failure

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13
Q

Primary pulmonary HTN most commonly affects middle-aged or young women. It is a defect in what gene?

A

BMPR2

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14
Q

Symptoms and PE findings of pulmonary HTN

A
  • Dyspnea, fatigue, cyanosis edema
  • Accentuated S2
  • Signs of right-sided HF: increased JVP, peripheral edema, ascites
  • Pulmonary regurgitation, right ventricular heave, systolic ejection click
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15
Q

Diagnostics for pulmonary HTN

A
  • CXR: enlarged pulmonary arteries, signs of right sided HF
  • ECG: Cor Pulmonale (RVH, right axis deviation)
  • Echo: large right ventricle, RVH
  • Right heart catheterization: DEFINITIVE
  • CBC: Polycythemia and increased hematocrit
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16
Q

In a primary pulmonary HTN case, what is the initial treatment?

A

-Vasoreactivity trial with inhaled Nitric oxide, IV Adenosine or CCB

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17
Q

And if the patient is vasoreative, what are the first line medications

A

CCB (first line)

  • Prostacyclins (Esoprostenol)
  • PD5-inhibitors (Sildenafil)
  • Oxygen therapy
  • Long term anticoagulation in some
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18
Q

What is the definitive treatment in pulmonary HTN

A

-Heart-lung transplant

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19
Q

70% of pulmonary embolisms arise from

A

deep vein in the legs (majority of the rest are from pelvic veins)

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20
Q

Risk factors for a DVT?

A
  • Virchow’s Triad
  • -Intimal damage: trauma, infection, inflammation
  • -Hypercoagulability: Protein C or S deficiency, Factor V Leiden, OCP, Pregnancy, Smoking
  • -Stasis: immobilization, surgery, sitting > 4 hours
21
Q

Symptoms of a PE

A
  • Sudden onset of dyspnea + pleuritic chest pain + hemoptysis
  • Tachypnea, tachycardia, fever
  • Positive Homan Sign (not specific)
22
Q

a CXR is the first diagnostic ordered to evaluate chest pain. What is highly suspicious of a PE?

A

-Normal CXR in the setting of hypoxia

23
Q

However, what are other classic but rare findings of a PE on a CXR?

A
  • Westermark’s Sign: avascular markings distal to the PE

- Hampton’s Hump: wedge-shaped infiltrate due to infarction

24
Q

What does an ECG show in a PE?

A

Nonspecific ST/T changes and sinus tachycardia most commonly

-Right heart dysfunction: S1Q3T3 (wide deep S in lead 1; isolated Q and T wave inversion in III)

25
What ABG is seen in a PE?
Respiratory alkalosis (secondary to hyperventilation
26
When is a D-dimer helpful in a PE diagnostics?
-Only if negative and a low-suspicion for PE
27
What are the confirmatory tests for a PE?
- Helical (spiral) CT angiography: best initial test to confirm PE - V/Q scan: used when CT cannot be performed (pregnancy, increased Creatinine) - Pulmonary angiography: GOLD STANDARD DEFINITIVE
28
Treatment for a PE if the patient is hemodynamically stable
-Anticoagulation: Heparin bridge + Warfarin or Dabigatran, Rivaroxaban, Apixaban
29
When do you use an IVC filter if the patient is stable?
- Anticoagulation is contraindicated (recent bleed, bleeding disorder) - Anticoagulation is unsuccessful (INR 2-3 on Warfarin, PE despite anticoagulation) - if RV dysfunction is seen on Echo
30
In a hemodynamically unstable patient (SBP < 90, RV dysfunction), what is the treatment for a PE?
- Thrombolysis | - Thrombectomy or Embolectomy: unstable or massive PE if thrombolysis contraindicated or ineffective
31
What is the Well's Criteria for a PE?
- 3 points added - -Signs and symptoms of DVT - -PE is #1 diagnosis or likely - 1.5 points added - -Heart rate > 100 - -Immobilization at least 3 days OR surgery in past 4 weeks - -previous DVT or PE - 1 point added - -Hemoptysis - -Malignancy with treatment within 6 months
32
Point Scoring System for Well's Criteria
- Low probability of PE: < 2 points = May consider D-dimer - Moderate probability of PE: 2-6 points = CTA or high-sensitivity D-dimer - High probability of PE: > 6 points = CTA
33
What are the three categories of PE Prophylaxis?
- Early ambulation: low risk, minor procedures in patients < 40 - Elastic stockings/compression stockings/boots: moderate risk - LMWH: orthopedic or neurosurgery, trauma
34
Risk factors for sleep apnea
- Obesity (strongest) - Age (60's and 70's) - Male Gender
35
Symptoms of Sleep Apnea
- Snoring, unrestful sleep --> daytime sleepiness - Nocturnal choking - Large neck circumference, crowded oropharynx, micrognathia (small lower jaw)
36
What is the first-line diagnostic for sleep apnea?
In-laboratory polysomnography (15 or more events per hour)
37
What is also used to quantify person's perception of sleepiness and fatigue?
Epworth Sleepiness Scale
38
Management of sleep apnea
- Behavioral changes: weight loss, no ETOH, change in sleep positioning - CPAP is mainstay of treatment - oral appliances if CPAP doesn't improve - Tracheostomy is definitive!
39
Neonatal Respiratory Distress Syndrome is from
- Insufficiency of surfactant production by an immature lung | - Primarily a lung disease in premature infants
40
What is the MCC of death in first month of life
-Neonatal respiratory distress syndrome
41
Surfactant production begins ______ weeks and by _____ weeks, enough surfactant is produced
24-28 weeks by 35 weeks enough is produced
42
Risk factors for Neonatal Respiratory Distress Syndrome
- Caucasians - Males - Multiple births - Maternal Diabetes - C-section delivery - perinatal infections
43
What is seen on CXR for neonatal respiratory distress?
-Bilateral diffuse reticular (ground glass) opacities + air bronchograms
44
Treatment for neonatal respiratory distress syndrome?
- Exogenous surfactant via endotracheal tube to open alveoli | - CPAP
45
How to prevent neonatal respiratory distress syndrome
Antenatal glucocorticoids given to mature lungs if premature delivery expected (between 24-36 weeks)
46
What are some signs of increased risk of a solitary pulmonary nodule?
- Spiculated (radial shadow, like spokes) - large ( > 2 cm) - Irregular borders - Asymmetric calcification - Upper lobe location - > 40 years of age - Smoker - Abnormal PET scan
47
What are some signs of decreased risk of a solitary pulmonary nodule?
- Well circumscribed smooth borders - Small < 1 cm - Dense diffuse calcifications - < 30 years old - Nonsmoker - No change in size - Normal CT scan
48
Diagnostic imaging for a solitary pulmonary nodule
- CXR: initial test that revealed nodule - CT chest: to determine if malignant - PET scan: to determine metabolic functioning of nodule