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Flashcards in Pysch Drugs Deck (45)
1

Preferred drug(s) for alcohol withdrawal

Benzodiazepines

2

Preferred drug(s) for anxiety

SSRIs, SNRIs, buspirone

3

Preferred drug(s) for ADHD

Methylphenidate, amphetamines

4

Preferred drug(s) for bipolar disorder

"Mood stabilizers" (e.g. lithium, valproic acid, carbamazepine), atypical antipsychotics

5

Preferred drug(s) for bulimia

SSRIs

6

Preferred drug(s) for depression

SSRIs, SNRIs, TCAs, buspirone, mirtazapine (especially with insomnia)

7

Preferred drug(s) for OCD

SSRIs, clomipramine

8

Preferred drug(s) for panic disorder

SSRIs, venlaxafine, benzodiazepines

9

Preferred drug(s) for PTSD

SSRIs

10

Preferred drug(s) for schizophrenia

Antipscyhotics

11

Preferred drug(s) for social phobias

SSRIs

12

Preferred drug(s) for Tourette's

Antipsychotics (e.g. haloperidol, risperidone)

13

Drugs classified as typical antipsychotics

Haloperidol and the "-azines"

14

MOA of typical antipsychotics

Block dopamine D2 receptors (increases cAMP)

15

SE of typical antipsychotics

EPS side effects (dyskinesias), endocrine side effects (galactorrhea)

Side effects arising from blocking muscarinic (dry mouth, constipation), alpha-1 (hypotension), and histamine (sedation) receptors

16

Symptoms of neuroleptic malignant syndrome caused by typical antipsychotics

Think FEVER

Fever
Encephalopathy
Vitals unstable
Elevated enzymes
Rigidity of muscles

17

Treatment of neuroleptic malignant syndrome

Dantrolene, D2 agonists (bromocriptine)

18

Symptoms of tardive dyskinesia caused by typical antipsychotics

Stereotypical facial movements as a result of long-term antipsychotic use, often irreversible

19

Typical antipsychotic that can cause corneal deposits

Chlorpromazine

20

Typical antipsychotic that can cause retinal deposits

Thioridazine

21

Drugs classified as atypical antipsychotics

Olanzapine, clozapine, quetiapine, risperidone, aripiprazole, ziprasidone

22

MOA of atypical antipsychotics

Varied effects on 5-HT2, dopamine, and alpha and H1 receptors

23

Atypical antipsychotic associated with agranulocytosis and seizures

Clozapine

24

Atypical antipsychotic associated with prolonged QT interval

Ziprasidone

25

MOA of buspirone

Stimulates 5-HT1A receptors, takes 1-2 weeks to take effect

26

Indication of buspirone

Generalized anxiety disorder

27

Drugs classified as SSRIs

Fluoxetine, paroxetine, sertraline, citalopram

28

SE of SSRIs

GI distress, sexual dysfunction (anorgasmia and decreased libido)

Serotonin syndrome: with any drug that increases serotonin resulting in hyperthermia, confusion, myoclonus, cardiovascular collapse, flushing, diarrhea, seizures

29

Treatment of serotonin syndrome

Cyproheptadine (5-HT2 receptor antagonist)

30

Drugs classified as SNRIs

Venlafaxine, duloxetine

31

SNRI that can be used to treat diabetic peripheral neuropathy

Duloxetine

32

SE of SNRIs

Increased BP, sedation, nausea, risk of inducing mania

33

Drugs classified as TCAs

Amitryptyline, nortriptyline, imipramine, desipramine, clomipramine, doxepin, amoxapine

34

MOA of TCAs

Block reuptake of NE and serotonin

35

TCA that can be used to treat bedwetting

Imipramine

36

TCA that can be used to treat OCD

Clomipramine

37

SE of TCAs

Postural hypotension, atropine like effects (tachycardia, urinary retention, dry mouth)

Tri-C's: Convulsions, Coma, Cardiotoxicity

38

Treatment of TCA cardiovascular toxicity

NaHCO3

39

Drugs classified as MAOIs

Tranycypromine, phenelzine, isocarboxazid, selegiline (selective MAO-B inhibitor)

40

MOA of MAO-Is

Nonselective MAO inhibition increases levels of amine neurotransmitters (NE, serotonin, dopamine)

41

SE of MAO-Is

Hypertensive crisis (most notably with ingestion of tyramine in wines and cheeses), CNS stimulation

42

MOA of mirtazapine

Alpha-2 antagonist (increases release of NE and serotonin) and potent 5-HT2 and 5-HT3 receptor antagonist

43

MOA of maprotiline

Blocks NE reuptake

44

MOA of trazodone

Inhibits serotonin reuptake

45

SE of trazodone

Sedation, nausea, priapism, postural hypotension