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Pharmacology 2 > Reproduction > Flashcards

Reproduction Flashcards

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1
Q

Which drug is used to treat premature labor in mares?

A

Altrenogest

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1
Q

What are clinical uses for prolactin inhibitors?

A

Mismating in the bitch and queen Pseudopregnancy in the bitch or queen

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1
Q

What is used to treat aglactica?

A

Dopamine antagonists - phenothiazines, metoclopramide, domperidone

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1
Q

What class of drugs is used to treat pituitary dwarfism in dogs?

A

Somatotropin

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2
Q

Treatment of benign prostate hypertrophy in dogs?

A

Castration

Megesterol acetate (inhibits gonadotropins)

Finasteride (inhibits 5 a-reductase)

GnRH antagonists

Large doses of GnRH agonists

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3
Q

What are the major side effects of progestin use?

A

CEH (cystic endometrial hyperplasia) Pyometra

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3
Q

What drug is used to induce abortion in cattle from day 7-150?

A

Prostaglandins

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4
Q

Synchronization of estrus in cattle and controlling the time of estrus in mares?

A

Prostaglandins

Progestins

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4
Q

T/F: There is no treatment for pseudopregnancy in the bitch.

A

True

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5
Q

Progestin approved in bitches?

A

Megestrol acetate

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5
Q

What is the DOC for induction of parturition in cattle in the last month of pregnancy?

A

Dexamethasone

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6
Q

Increasing luteal formation in large animals?

A

GnRH

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6
Q

What drugs are prolactin inhibitors?

A

Bromocriptine

Cabergoline

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6
Q

What drug is used for chemical castration in dogs?

A

Zinc glutonate neutralized with arginine by injection (3-10 months of age)

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7
Q

What are our androgen drugs?

A

Testosterone esters Trenbolone Mibolerone

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9
Q

Diagnosis of LH and testosterone deficiency in small animals?

A

GnRH

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9
Q

What drug is used to stimulate uterine contraction?

A

PGF2a
Estrogens
Oxytocin

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10
Q

What effect to prostaglandins have on the corpus luteum?

A

Regression of the CL by increased intracellular free calcium

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10
Q

Term to describe mismating in large animals?

A

Abortifacient

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11
Q

What are the uterine stimulants?

A

Estrogens Oxytocin PGF2a Glucocorticoids Ergonovine

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11
Q

What drugs cause ejaculation in stallions?

A

Imipramine Xylazine (a2 agonist) PGF2a

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12
Q

Term to describe induction of parturition?

A

Ecbolic (oxytocic)

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12
Q

What is the DOC to induce parturition in the bitch and mare?

A

Oxytocin

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13
Q

What estrogen is used on its own for growth promotion in cattle and sheep?

A

Zeranol

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14
What drug is combined with a progestin for estrus synchronization in cattle?
Estradiol valerate
16
Treatment of cryptorchidism in dogs?
hCG
17
Which drugs are used for contraception and suppression of estrus in small animals?
Megestrol acetate in bitches and queens
18
Administration of what drug before prostaglandins will reduce side effects in small animals?
Atropine
19
What drug should be used to induce abortion in the last month of pregnancy in cattle?
Dexamethasone or PGF2a
21
What drugs can be used as implants in feedlot heifers and steers?
Testosterone-estradiol Trenbolone
21
What are our anabolic steroids?
Stanozolol Boldenone
22
What species is Stanozolol approved in?
Dogs, cats, horses
23
Stimulation of testosterone secretion in large animals?
hCG
23
Androgen antagonists in prostate hypertrophy and tumors, and anal adenoma?
Estrogens
23
Treatment of silent estrus and pyometra in cattle?
Prostaglandin
23
Term to describe mismating in small animals?
Antinidatory
23
Androgens or estrogens used for pseudopregnancy in the bitch?
Testosterone cypionate Mibolerone DES
24
Class of drugs used to maintain pregnancy and promote estrus?
Progesterones
25
What class of drugs increase milk production and enhance growth in large animals?
Somatotropin
26
What are the adverse effects of prostaglandins in horses?
Sweating and colic
27
DOC to expel mummified fetuses in large animals?
Prostaglandins
28
Induction of parturition in swine and cattle?
Prostaglandins
29
What drug is used to decrease serum progesterone?
PGF2a
31
Progestin approved in cattle?
Melengestrol acetate
32
Drug used to suppress estrus and synchronization of estrous cycle?
Progesterone CIDR in cattle Altrenogest in mares Norgestomet implants and norgestomet-estradiol valerate injection in beef cattle and non-lactating heifers
33
T/F: and ovarian historectomy should be performed during clinical signs of pseudopregnancy.
False
35
Induction of ovulation in the mare?
hCG GnRH - specifically Deslorelin acetate
36
Treatment of pyometra in large animals with antibiotics?
Prostaglandins
38
What drug is used to produce a teaser to identify cows in estrus?
Testosterone
39
Induction of ovulation in cats?
hCG
41
Progestin approved in cats?
Hydroxyprogesterone caproate
42
What class of drugs inhibit uterine contraction?
Tocolytics
43
What synthetic prostaglandins are approved in mares?
Fluprostenol
44
What drug is used in combination with progesterone or testosterone for growth in cattle?
Estradiol
45
DOC for endophyte-induced agalactia in mares?
Domperidone
47
Adverse effect of using estrogens in mismating in small animals?
Pyometra
49
Prostaglandins have no side effects in what two species?
Swine Cattle
49
Induction of parturition in sows?
PGF2a alone or with Oxytocin
50
What drugs are listed under tocolytics?
Beta 2 agonists (terbutaline, ritodrine) Magnesium sulfate Inhalation anesthetics
51
Induction of parturition in cattle?
Glucocorticoids PGF2a
53
What do prostaglandins activate?
Protein kinase C
55
Stimulation of follicular growth in anestrous animals
eCG
57
Induction of estrus in the bitch?
Estrogens
57
During the first 150 days of gestation, what should be used to induce abortion in cattle?
PGF2a or its analogs
58
What drugs can be used to treat pseudopregnancy in the bitch?
Mibolerone Testosterone
60
Treatment of mismating in dogs and cats?
Estrogens (not recommended - can cause pyometra)
62
What is our mycotoxin estrogen?
Zeranol
63
What is one of the most common reproductive problems during diestrus in the bitch?
Pseudopregnancy
65
What species are PGF2a tham salt and dinoprost trimethamine approved in?
Cattle Mares Sows
67
Treatment of mismating in the bitch?
Prostaglandins
68
Treatment of urinary incontinence, dermatitis, and vaginitis in the ovarectomized bitch and queen?
Estrogens
69
Dopamine agonists used for pseudopregnancy in the bitch?
Bromocriptine Cabergoline A.K.A. Prolactin inhibitors
70
What synthetic prostaglandins are approved in cattle?
Cloprostenol Fenprostalene
71
What drug should be used to induce abortion at 5-8 months gestation in cattle?
Combination of PGF2a and dexamethasone
73
Induction of estrus in prepubertal gilts?
eCG in combination with hCG
74
Induction of super ovulation in cattle?
eCG in combo with PGF2a
75
Increasing libido in male dogs and cats?
GnRH
76
What is the most serious reproductive problem in the bitch?
CEH
77
Induction of parturition in small animals?
Oxytocin
78
What class of drugs is used to treat GH-responsive dermatosis in small animals?
Somatotropin
80
Treatment of follicular cysts in cattle?
Human chorionic gonadotropin (hCG) GnRH
81
What species is Boldenone approved in?
Horses
82
Treatment of follicular cysts in the bitch?
hCG GnRH
83
Drugs used as growth promoters in cattle?
Progesterone-estradiol benzoate Melengesterol
84
Progestin approved in mares?
Altrenogest
85
Progestin approved in beef cattle and non lactating heifers?
Norgestomet implants and norgestomet-estradiol valerate injection Syncro Mate B
86
What is our synthetic non steroidal estrogen?
DES
88
What are our Estradiol esters?
Cypionate Propionate Benzoate Velerate
89
What do prostaglandins inhibit?
Steroid synthesis
90
Induction of parturition in the mare?
Oxytocin
91
Treatment of uterine infections in the bitch or queen?
Prostaglandins
92
Which prolactin inhibitor is better?
Cabergoline
93
Which drugs are used to treat behavioral problems and urination in male cats?
Hydroxyprogesterone caproate Medroxyprogesterone acetate
94
What drugs can be used to treat suppression estrus in dogs?
Milbolerone Testosterone

Pharmacology 2 (13 decks)

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