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Flashcards in SBA 3 Mock Deck (43)
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1

COPD spirometry results

FEV <80% predicted

FEV1/FVC <0.7

COPD = Obstructive

2

Pharmacological management of adult diagnosed with asthma

1. SABA - Salbutamol
2. Low ICS - beclomethasone
3. LTRA - Montelukast
4. LABA - Salmeterol

5. MART = ICS + fast-LABA

6 Mod ICS
7. High ICS

3

What would indicate that a pt should add ICS to their asthma management?

If they:

- use SABA > 2/week +/- asthma symptoms

- use SABA >2/week +/- woken at night by asthma weekly

4

Which lung cancer is strongly associated with cigarette smoking?

Small Cell Carcinoma

5

Which lung cancer is most common in NON-SMOKERS? Any risk-factors?

Adenocarcinoma

RF: Asbestos exposure

6

Common sites for lung cancers to metastasise to?

Adrenal glands
Bone
Brain
Liver
Lymph nodes

7

Common site for breast cancer to metastasise to?

Lungs

(but lung cancer does not usually metastasise to breast)

8

Pt is a 55yr old pilot. He is a smoker. He has noticed pain and swelling in his right calf for weeks but has ignored it. He now has pain in his chest.

Gold standard investigation for likely diagnosis? What RF does he have?

CT Pulmonary Angiogram

Likely diagnosis: Pulmonary Embolism

His RF:
- Likely DVT
- Long flights
- smoking

9

Most common causes of typical pneumoniae in both the community and hospital

TYPICAL CAP
1. Strep pneumonia

TYPICAL HAP
1. Staph aureus

COPD
1. Haemophilus influenza B

10

Causes of atypical bacterial pneumoniae

Are they detectable on gram stain?

Mycoplasma pneumonia

Chlamydophila pneumonia

Legionella pneumonia

- Not detectable on gram stain

11

Most common cause of pneumonia in COPD patients

Haemophilus influenza B

12

CURB-65 parameters and use

CAP Severity

Confusion
Urea >7
RR >30
BP s<90 or d<60

>65

13

TB Management and side effects

4 for 2, 2 for 4 RIPE

Rifampicin - Red/orange
Isoniazid - peripheral neuropathy (give pyridoxine)
Pyrazinamide - uric acid: arthralgia, gout, rash
Ethambutol - Eyes; Optic neuritis

14

Chromosome 7 mutation

Cystic Fibrosis

c/s 7 codes CFTR protein > defective Cl- secretion/ Na+ absorption

15

Chromosome 6 mutation

Hereditary Haemochromatosis

16

Chromosome 13 mutation

Wilson's disease

17

Chromosome 14 mutation

Alpha-1 Antitrypsin deficiency

18

Chromosome 21 mutation

Trisomy - Down's syndrome

19

29-F presents with painless genital ulcer. She had unprotected sex with a new partner in the last 6 months.

EIA IgM is positive for syphilis. She has no allergies; she is not pregnant.

Management?

Primary Syphilis

1L: Benzathine penicillin

2L: Azithromycin/ Doxycycline (if penicillin-allergic)

20

Below are the underlying causes of Raynaud's syndrome. What features differentiate them?

1. Carpal Tunnel
2. Dupuytren's contracture
3. SLE
4. Hand arm vibration syndrome

1. Carpal Tunnel - median nerve distribution weakness, tingling

2. Dupuytren's contracture - permanently flexed digits

3. SLE - young, autoimmune, rash

4. Hand-arm vibration - power tools

21

Pt presents with tingling, weakness and aching of his hands. He works an office job.

Likely diagnosis?

Repetitive Strain Injury

22

Meningitis management

- primary care
- hospital care
- prophylaxis

Primary care: Benzylpenicillin (if non-blanching rash)

Hospital:
1. IV Ceftriaxone
2. a) Amoxicillin - Neisseria
b) Ampicillin - Listeria (young, old, immunosuppressed)
c) Vancomycin - Strep pneumonia
d) Acyclovir - Viral
<3months - IV Cefotaxime + ampicillin/amoxicillin

Prophylaxis
1. Ciprofloxacin
2. Rifampicin

23

Bacterial causes of meningitis

Strep pneumonia
Neisseria meningitides
Haemophilus influenza
Listeria monocytogenes

SHiLN

24

Viral causes of meningitis

Enterovirus - Echo/Coxsackie
HSV
Measles, Rubella

25

Fungal causes of meningitis

Cryptococcus neoformans

Mycobacterial

26

Chemoprophylaxis for meningitis

Ciprofloxacin
Rifampicin

27

Most common work-related ill-health in the UK

#1 Stress, anxiety, depression

#2 MSK conditions

28

Define sensitivity

The proportion of patients who have the disease AND test positive

29

Define specificity

The proportion of patients who don't have the disease AND test negative

30

Define positive predictive value

The proportion of patients who test positive who have the condition