SCHIZOPHRENIA

Question 1

What is schizophrenia?

Answer 1

A severe mental disorder, characterised by profound distrubtion in thinking, affecting language, perception and the sense of self

Question 2

Who did the first formal description of symptoms of schizophrenia?

Answer 2

Emil kraepelin

Question 3

What did eugene bluer do?

Answer 3

First used term schizophrenia
Schizophrenia: splitting (schizo) of the mind (phrenia)

Question 4

Negative problems with schizophrenia?

Answer 4

Avolition
Anhedonia
Associality

Characterised by a reduction in normal behaviour

Question 5

Whats the cognitive problems with schizophrenia?

Answer 5

Disturbances of attention, memory and executive cognitive function

Characterised by changes in memory, attention and executive function

Question 6

Positive problems with schizophrenia?

Answer 6

Hallucinations
Delusions
Thought derailment

Characterised by behaviours over and above normal behaviours

Question 7

Whats the diagnosis for schizophrenia in the us called?

Answer 7

Diagnostic and stastical manual DMS

Question 8

Whats the diagnosis of schizophrenia in Europe?

Answer 8

International classifications of diseases ICD

Question 9

Phenomenology of schizophrenia?

Answer 9

Symptomatology differs greatly between patients
Sympatomatology in individual patietns show periodic fluctuations

Question 10

Whats the prevalence rate for schizophrenia?

Answer 10

Approximately 0.5% - 5 per 1000 people surveyed per year
Peak onset in late adolescence and early adulthood 20-39 years

Evidence suggests that genetic, biological and social aspects are important in determining schizophrenia onset

Question 11

Evidence of genetic influence?

Answer 11

• patients and siblings of sufferers 10 times more likely
• children of sufferers 15 times more likely
• concordance rate in identical twins - 40-50%
• concordance rate in fraternal twins - 5-10%
• entirely genetic: concordance rates in twin would be identical 100% and fraternal 50%
  Therefore there is a strong genetic component, but it is not entirely genetically determined

Question 12

Whats the exclusion criteria?

Answer 12

Mood disorder, drug taking , neurological conditions

Question 13

Environmental factor affecting schizophrenia?

Answer 13

Biological factors
• Prenatal exposure to viruses (2nd trimester of pregnancy)
• high incidence in people born after major ‘flu epidemics
• high incidence in people born in the spring

Pregnancy and delivery complications
• high incidence in people who had forceps deliveries

Social factors
- life experiences
- family relationships, upbringing

May trigger the diseasein people with a genetic predisposition

Question 14

ORGINS of schizophrenia?

Answer 14

Genetic biological and upbringing