Semester Exam: membrane functions/structures Flashcards

1
Q

plasma membrane

A

lipid and protein bilayer, changing fluid mosaic

seperates intrecellular and extracellular fluid

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2
Q

membrane lipids

A

phospholipids
glycolipids
cholesterol

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3
Q

phospholipids

A

Phosphate heads: polar and hydrophilic

Fatty acid tails: nonpolar and hydrophobic

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4
Q

glycolipids

A

Lipids with polar sugar groups on outer membrane surface

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5
Q

cholesterol

A

Increases membrane stability and fluidity

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6
Q

integral proteins

A

inserted in membrane, function transporting proteins, enzymes, or receptors

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7
Q

peripheral proteins

A

loosely attached to integral proteins

Include filaments on intracellular surface and glycoproteins on extracellular surface

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8
Q

peripheral proteins function

A

enzymes, motor proteins, support

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9
Q

functions of membrane proteins

A

Transport
Receptors for signal transduction
Attachment to cytoskeleton and extracellular matrix

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10
Q

membrane junctions three types

A

tight
desmosome
gap

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11
Q

tight junctions

A

Impermeable junctions Prevent fluids and most molecules from moving between cells

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12
Q

desmosomes

A

rivets that anchor cells together

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13
Q

gap junctions

A

Transmembrane proteins form pores that allow small molecules to pass from cell to cell, communicating junctions

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14
Q

passive transport

A

No cellular energy (ATP) required

Substance moves down its concentration gradient

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15
Q

active transport

A

Energy (ATP) required

Occurs only in living cell membranes

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16
Q

What determines whether or not a substance can passively permeate a membrane?

A

Lipid solubility of substance
Channels of appropriate size
Carrier proteins

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17
Q

passive transport types

A

Simple diffusion
Carrier-mediated facilitated diffusion
Channel-mediated facilitated diffusion
Osmosis

18
Q

Simple Diffusion

A

Nonpolar lipid-soluble (hydrophobic) substances diffuse directly through the phospholipid bilayer

19
Q

Facilitated Diffusion

A

Certain lipophobic molecules (e.g., glucose, amino acids, and ions) use carrier proteins or channel proteins

20
Q

both channel proteins and carrier proteins

A
Exhibit specificity (selectivity)
Are saturable; rate is determined by number of carriers or channels
21
Q

Facilitated Diffusion Using Carrier Proteins

A

Transmembrane integral proteins transport specific polar molecules (e.g., sugars and amino acids)
Binding of substrate causes shape change in carrier

22
Q

Aqueous channels formed by transmembrane proteins selectively transport

A

ions or water

23
Q

Facilitated Diffusion Using Channel Proteins two types

A

Leakage channels
Always open
Gated channels
Controlled by chemical or electrical signals

24
Q

osmosis

A

Movement of solvent (water) across a selectively permeable membrane

25
Water diffuses through plasma membranes:
Through the lipid bilayer | Through water channels called aquaporins
26
osmolarity
`The measure of total concentration of solute particles
27
tonicity
The ability of a solution to cause a cell to shrink or swell
28
Isotonic
A solution with the same solute concentration as that of the cytosol
29
Hypertonic
A solution having greater solute concentration than that of the cytosol
30
Hypotonic
A solution having lesser solute concentration than that of the cytosol
31
cells in isotonic solution
Cells retain their normal size and shape in isotonic solutions (same solute/water concentration as inside cells; water moves in and out).
32
cells in hypertonic solution
``` Cells lose water by osmosis and shrink in a hypertonic solution (outside contains a higher concentration of solutes than are present inside the cells) ```
33
cells in hypotonic solution
``` Cells take on water by osmosis until they become bloated and burst (lyse) in a hypotonic solution (outside contains a lower concentration of solutes than are present in cells). ```
34
Cotransport
always transports more than one substance at a time
35
Symport system
Two substances transported in same direction
36
antiport system
Two substances transported in opposite directions
37
vesicular transport
Transport of large particles, macromolecules, and fluids across plasma membranes Requires ATP
38
Exocytosis
out of cell
39
endocytosis
into cell
40
transcytosis
transport into,across, and then out of cell
41
Phagocytosis
pseudopods engulf solids and bring them into cell’s interior | food, macrophages, white blood cell
42
pinocytosis
bringing extracellular fluid and solutes into interior of the cell Nutrient absorption in the small intestine