STAPHYLOCOCCUS Flashcards

1
Q

staphylococcus come from the greek term STAPHILE means

A

bunches of grapes

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2
Q

colony morphology of staphylococcus

A

cream colored, white, or rarely light gold, buttery-looking

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3
Q

staphylococcus resemble some members of the family micrococcaceae such as the genus __

A

micrococcus

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4
Q

staphylococcal species can be initially differentiated by __ test

A

coagulase test

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5
Q

what are the staphylocoagulase-produsing genus

A

aureus
intermedius
pseudointermedius
hyicus
delphini
lutrae
agnetis
some strain of schleiferi

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6
Q

causes bacterial cells to agglutinate in plasma and was the basis of a test known as the slide coagulase test

A

clumping factor

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7
Q

is the most clinically significant species of staphylococcus

A

Staphylococcus aureus

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8
Q

superficial infection of S.aureus

A

impetigo and cellulitis

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9
Q

subcutaneous infection of S.aureus

A

carbuncles

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10
Q

systemic and organ infection of S.aureus

A

bacteremia and septicemia

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11
Q

a commmon cause of infective endocarditis and toxin-induced disease such as food poisoning, and is associated with scalded skin syndrome and toxic shock syndrome

A

staphylococcus aureus

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12
Q

SSS and TSS

scalded skin syndrom and toxic shock syndrome

A

S. aureus

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13
Q

which staphylococcus has been known to cause various healthcare acquired or nosocomial infections

A

staphylococcus epidermidis

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14
Q

which staphylococcus has been associated mainly with UTI

A

S.saprophyticus

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15
Q

which staphylococcus has been occasionally recovered from wounds, septicemia, UTI, and native valve infections

A

S.haemolyticus

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16
Q

which staphylococcus has been known as an aggressive pathogen and has been associated with catheter-related bacteremia and endocarditis

A

S. lugdunensis

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17
Q

virulence factors of S.aureus

A

enterotoxins
cytolytic toxins
protein A

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18
Q

Staphylococcal food poisoning is most commonly caused by what enterotoxins of S.aureus

A

A, B, and D

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19
Q

the enterotoxins of S.aureus are produced by ___ to __% of S.aureus

A

30%-50%

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20
Q

enterotoxins of S.aureus are stable at 100*C for how many mns

21
Q

which enterotoxins of S.aureus are associated with TSS

A

B and C

sometimes G and I

22
Q

exfoliative toxin is also known as

A

epidermolytic toxin

23
Q

2 types of exfoliative toxin of S. aureus

24
Q

they cause the epidermal layer of the skin to slough off and are known to cause staphylococcal SSS

A

exfoliative toxin

25
exfoliative toxin they cause the epidermal layer of the skin to slough off and are known to cause staphylococcal SSS this disease is sometimes referred to as
ritter disease
26
this toxin of S.aureus has also been implicated in bullous impetigo
exfoliative toxin
27
hemolysin of S.aureus that causes lysis to erythrocytes, damage platelets, and macrophages, and cause severe tissue damage
a-hemolysin
28
hemolysin of S.aureus that acts on sphingomyelin in the plasma membrane of erthrocytes and is called the "hot-cold" lysin
b-hemolysin
29
gamma hemolysin is found only in associated with ____
panton-valentine leukocidin (PVL)
30
is an exotoxin lethal to polymorphonuclear leukocytes
PVL - panton valentine leukocidin
31
hemolysin of S.aures responsible for CAMP assay effectiveness
B hemolysin
32
enzyme of s.aureus that cleaves the ring structure of penicillins and derivative antibiotic, making them ineffective
b-lactamase
33
altered membrane binding protein resulting in resistance to some b lactam-antibiotics
penicillin binding protein 2
34
enzyme of S,aureus that permits it to spread through connective tissues
hyaluronidase
35
enzyme of S,aureus that degrades lipids on the skin surface, making it more susceptible to bacterial entry intro epidermal layers
lipases
36
enzyme of S,aureus responsible for a posotiv etube coagulase test result
staphylocoagulase
37
a toxin of S.aureus which is considered a `superantigen` causing an overreactive immune response
TSS toxin-1
38
TSS toxin-1 is formerly knoiwn as
asenterotoxin F
39
virulence factor of S.aureus that binds IgG and prevents phagocytosis
PROTEIN A
40
types of epidermolytic toxin/exfoliative toxin that is solely responsible for SSS
A and B
41
benign skin infection of S.aureus
folliculitis furuncles bullous impetigo
42
is a relatively mild inflammation of a hair follicle or oil gland
folliculitis
43
in contrast with furuncles, patients with __ often present with fever and chills, indicating systemic spread of the bacteria
carbuncles
44
is staph SSS same with TEN - toxic epidermal necrolysis?
nope, TEN has multiple causes but is most commonly associated with drug reactions, linked to antmicrbials and anticonvulsives
45
a rare but potentially fatal, multisystem disease characterized by sudden onset of fever, chills, vomiting, diarrgea, muscle aches, and rash, which can quickly progress to hypotension and shock
TSS - toxic shock syndrome
46
remains the treatment of choice for MRSA infection
vancomycin
47
is frequently used in staphylococcal skin infectios,
clindamycin
48