synapse Flashcards

1
Q

what is a synapse

A
  • the very small gap between adjacent neurons
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2
Q

what direction do synapses occur?

A

from axon to dendrite/cell body

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3
Q

what is the first step of a synapse?

A
  • AP arrives at pre synaptic terminal and triggers voltage gated calcium channels to open
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4
Q

what is the second step of a synapse?

A
  • causes calcium to rush into presynaptic terminal via conc gradient
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5
Q

what is the third step of a synapse?

A
  • calcium binds to vesicle and triggers it to migrate towards synapse
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6
Q

what is the fourth step of a synapse?

A
  • vesicle binds to membrane and excretes neurotransmitters by exocytosis
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7
Q

what is the fifth step of a synapse?

A
  • neurotransmitters diffuse across the clef and bind to chemically gated sodium channels on post synaptic terminal
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8
Q

what is the sixth step of a synapse?

A
  • this stimulates ligand-gated protein channels to open which allows influx of Na via conc gradient
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9
Q

what is the seventh step of a synapse?

A
  • an AP will be generated in the post synaptic membrane
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10
Q

what is the eighth step of a synapse?

A
  • neurotransmitters will be reabsorbed into a presynaptic cleft or broken down by enzyme action
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