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Tumor De Wilms Flashcards

(10 cards)

1
Q

TUMOR DE WILMS

Alteraciones genéticas

A

Alteraciones cromosoma 11, gen TW1 y TW2

65% tumores anaplasicos tienen mutaciones TP53

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2
Q

Síndrome de WAGR

A

Wilms
Aniridia
Malformaciones genitorurinarias
Retraso mental

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3
Q

Anomalías genitourinarias asociadas al tumor de Wilms

A

Hipospadias
Criptorquidia
Duplicación sistemas colectores
Malformaciones renales
Aniridia

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4
Q

Síndrome de Beckwith Wiedemann

A

Hemihipertrofia
Macroglosia
Onfalocele
Visceromegalia
Hipoglucemia

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5
Q

TUMOR DE WILMS

Clínica

A

Masa abdominal asintomática
Dolor abdominal
Hematuria
Fiebre

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6
Q

TUMOR DE WILMS

Diagnóstico inicial

A

USG abdominal

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7
Q

TUMOR DE WILMS

Gold standard

A

TAC abdomen con doble contraste

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8
Q

TUMOR DE WILMS

Tratamiento

A

En todos los casos realizar nefrectomía y quimioterapia

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9
Q

TUMOR DE WILMS

Principal zona de metástasis

A

Pulmón

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10
Q

TUMOR DE WILMS

Estadificacion (NWTS)

A

I: Dentro, Solo en el riñón, cápsula intacta

II: Fuera del riñón, pero totalmente resecado

III: Quedó en abdomen (ganglios, márgenes +, ruptura)

IV: Voló, Metástasis a distancia

V: Doble, Bilateral

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