Unit 3- Chlamydia

Question 1

Reasons for Intracellularity

Answer 1

Protection from permeable cell membrane, ATP shortage, cholesterol demand

Question 2

Chlamydia and Coxiella Lifecycle

Answer 2

Spore like particle extracellularly, actively replicates inside host cells

Question 3

Chalmydia Intracellular

Answer 3

Reticulate inclusion bodies

Question 4

Coxiella Intracellular

Answer 4

Large cell variant

Question 5

Anaplasma and Ehrlichia Intracellular

Answer 5

Reticulate cells (morula)

Question 6

Chlamydia Extracellular

Answer 6

Elementary body

Question 7

Coxiella Extracellular

Answer 7

Small cell variant

Question 8

Anaplasma and Ehrlichia Extracellular

Answer 8

Dense cored cells

Question 9

Rickettsia Intracellular

Answer 9

Freely moves in cytoplasm without hiding in vacuoles

Question 10

Anaplasma Transmission

Answer 10

Ticks

Question 11

Ehrlichia Transmission

Answer 11

Ticks

Question 12

Rickettsia Transmission

Answer 12

Ticks, lice, mites, fleas

Question 13

Coxiella Transmission

Answer 13

Airborne

Question 14

Chlamydia Transmission

Answer 14

Airborne, sex, elementary body contagious transmission

Question 15

Mycoplasma Transmission

Answer 15

Airborne

Question 16

MAKePSR Syndrome

Answer 16

Mastitis, arthritis, keratoconjunctivitism, pneumonia, septicemia, reproductive disorder caused by chlamydia and mycoplasma tropism for mucous membranes

Question 17

Rickettsiales Predilection Sites

Answer 17

RBC, WBC, or blood vessels

Question 18

Iceberg Concept

Answer 18

Presence of clinical cases indicates huge members have subclinical infection, multiple species may be involved

Question 19

Chlamydia

Answer 19

Gram neg cocci, little peptidoglycan, giemsa stain best, obligate intracellular

Question 20

Why is Chlamydia obligate intracellular?

Answer 20

Cytoplasmic membrane highly permeable, cannot produce amino acids and ATP

Question 21

Chlamydia Elementary Body

Answer 21

Extracellular form, environmentally resistant, airborne, infects vertebrates

Question 22

Chlamydia Aberrant Body

Answer 22

Characterizes persistent infection, formed during stressful conditions from antimicrobials or host immune

Question 23

Chlamydia Hosts

Answer 23

Some interspecies transmission, wide variety of hosts

Question 24

Chlamydia Pathogenesis

Answer 24

Attacks columnar epithelium of epithelial cells and mucous membranes

Question 25

Chlamydiosis

Answer 25

MaKePSRRD syndrom

Question 26

Chlamydia abortus

Answer 26

Ovine abortion storms and placentitis, follicular vaginitis in cow

Question 27

Chlamydia Virulence Factors

Answer 27

Neuraminidase, catalase, protease, LPS, T3SS, intracellular survival

Question 28

Gold Standard Test for Chlamydia

Answer 28

Indirect immunofluorescent IgG antibody assay

Question 29

Chlamydia Culture

Answer 29

Requires living cell lines, chicken embryo, buffalo green monkey kidney cells

Question 30

Chlamydia Treatment

Answer 30

Antibiotics early in infection, induces aberrant bodies in persistent chlamydial infection

Question 31

Chlamydia abortus Vaccine

Answer 31

Prevents abortion in small ruminant

Question 32

Chlamydia felis Vaccine

Answer 32

Prevents keratoconjunctivitis in pets

Question 33

Chlamydia Groups

Answer 33

Avian, Mammalian, Human