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LA Clinical Medicine > Unit 3 - Neuro (CN, Reflexes, Diagnostics, Definitions) > Flashcards

Unit 3 - Neuro (CN, Reflexes, Diagnostics, Definitions) Flashcards

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1
Q

What are the four functionally different anatomic areas of the nervous system?

A

Cerebrum
Cerebellum
Brainstem and cranial nerves
Spinal cord and peripheral nerves

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2
Q

What are the three etiological categories of nervous illnesses?

A

Acquired biologic
Acquired nonbiologic
Congenital or hereditary

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3
Q

What should be observed on distant neurologic examination?

A

Mentation, posture, and gait

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4
Q

What spinal reflexes can be assessed in all ruminants?

A

Panniculus, withdrawal of forelimb/hind limb, patellar, and perineal reflex

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5
Q

What are the 6 broad types of abnormalities in mentation in ruminants?

A
  1. Excitement, mania, or hyperesthesia
  2. Seizures
  3. Depression
  4. Aimless circling, stupor, or coma
  5. Abnormal vocalization
  6. Blindness
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6
Q

T/F: Aimless circling and tight circles associated with vestibular lesions are caused by the same process.

A

False - aimless circling is due to serevral disease

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7
Q

What is gait?

A

The coordinated functioning of the cerebral cortex, extrapyramidal basal nuclei, and red nuclei which stimulates the flexor muscles and simultaneous inhibition of extensor muscles

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8
Q

What can cause gait abnormalities?

A

Cerebellar, brainstem, spinal cord, and peripheral nerve lesions

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9
Q

How do you assess conscious proprioception in ruminants?

A

During ambulation by placing obstacles in enclosures/alleyways

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10
Q

If an animal is halter broke, how do you assess conscious proprioception?

A

Walking in tight circles, walking across/up a curb, walking up and down a hill, and pulling the tail while walking strait

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11
Q

What neurologic signs can suggest the possible presence of proprioception deficits and exaggerated spinal reflexes?

A

Presence of ataxia, hypermetria, and truncal sway

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12
Q

What is posture maintained by?

A

The trunk muscles and extensor muscles of the proximal limbs

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13
Q

What facilitates posture?

A

The vestibulospinal and reticulospinal tracts from the medulla and pons

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14
Q

What are the three main aspects of posture?

A

Head, body, and limbs

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15
Q

What processes sensory input from pressure/stretch receptors in the limbs/body, vestibular system, and visual inputs?

A

The brainstem, cerebellum, and cerebrum

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16
Q

Abnormal head posture (continuous head tilt) indicates what?

A

Central or peripheral vestibular disease

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17
Q

What can cause abnormal trunk posture?

A

Congenital or acquired disorders such as scoliosis, lordosis, and kyphosis

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18
Q

What are some abnormal limb postures that can result from UMN or LMN disease?

A

Inappropriate positioning, weakness, knuckling, and a base-wide stance

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19
Q

What does the menace response evaluate?

A

The entire visual pathway, CN VII, and the cerebellum

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20
Q

What cranial nerves are involved in the menace response?

A

CN II and CN VII

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21
Q

T/F: The menace response is often absent in neonatal ruminants.

A

True

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22
Q

What cranial nerves do pupillary reflexes assess?

A

CN II and CN III

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23
Q

If the intraparenchymal visual pathways are affected (central or cortical blindness) what will the menace response be? The PLRs?

A

Menace - absent on the contralateral side of the lesion

PLR - intact

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24
Q

If the extraparenchymal visual pathways (peripheral blindness) are affected, what will the menace response be? PLRs?

A

Menace - blindness on the size of lesion; absent

PLRs - abnormal

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25
What muscles does the CN III control?
Dorsal, ventral, and medial rectus muscles Ventral oblique muscle Levator palpebrae muscle
26
What do lesions of CN III result in?
Ipsilateral ventrolateral strabismus and mydriasis
27
What muscle does CN IV innervate?
Dorsal oblique muscle
28
What do lesions of CN IV result in?
dorsolateral strabismus
29
What does CN VI innervate?
The lateral rectus and retractor bulbi muscles
30
What do lesions of CN VI result in?
Medial strabismus with a more forward positioning of the globe Failure to retract the globe during assessment of the palpebral (or corneal) reflex
31
T/F: The eyes of ruminants should try to maintain focus straight ahead, the result being that the eye moves slowly in the opposite direction of the head movement and then 'jump' quickly back towards the direction movement.
True
32
What are the three branches of the trigeminal nerve (CN V)?
Ophthalmic, maxillary, and mandibular
33
While all branches of CN V have sensory fibers, which branch has motor fibers as well?
Mandibular
34
Lesions to the mandibular branch of CN V result in what clinical signs?
Muscle asymmetry/loss, flaccid or lowered jaw, inability to close the jaw, inability/reduced mastication with dropping of feed and drooling, and protrusion of the tongue.
35
What do the corneal and palpebral reflexes test?
Sensory - CN V | Motor - CN VII
36
What branch of the trigeminal is assessed by touching the medial canthus? Lateral canthus?
Medial canthus - ophthalmic branch | Lateral canthus - maxillary branch
37
How is sensory function of the mandibular branch of CN V tested?
Touching/pinching the face, including the base of the ear
38
How is the consciously mediated, coordinated movement of the head away from noxious stimuli assessed?
Applying stimuli to the nasal septum
39
What CN tests test CN VII?
Menace response, palpebral reflex, corneal reflex
40
What does CN VII innervate?
Facial muscles of expression Parasympathetic innervation to the lacrimal gland, and mandibular and submandibular salivary glands Symmetry, posture, and movement of the eyelids, lips, and ears
41
What can lesions of CN VII cause?
Ear droop, lack of ear movement, eyelid droop (ptosis), and deviation of nasal philtrum Lack if muzzle tone can result in protrusion of the tongue and driiping Exposure keratitis
42
What is the vestibular portion of CN VIII responsible for?
maintaining head position and other structures relative to the pull of gravity
43
What is the cochlear division of CN VIII responsible for?
hearing
44
What are clinical signs associated with vestibular dysfunction?
Head tilt, nystagmus, ataxia, incoordination, positional strabismus, and head tilt towards the lesion (often will fall on the side of the lesion)
45
What do CN IX and CN X innervate?
Pharynx, larynx, and tongue Striated muscles of the esophagus CN X - abdominal viscera including the forestomach
46
How is the gag reflex performed?
Place a tongue depressor on the back of the tongue, which normally the animal should 'throw' back up
47
What does CN XII innervate?
Motor innervation of the tongue, controlling both protrusion and retraction
48
What signs are indicative of a CN XII lesion?
Difficult prehension and mastication feed Unilateral damage results in a tongue to twist toward the affected side (if it is a facial nerve lesion the tongue will twist away from the lesion)
49
Evaluation of spinal reflexes is best achieved in what position?
Lateral recumbency
50
T/F: Spinal reflexes require conscious or voluntary input and test the integrity of LMN, but also provide information on UMN influence on LMN
False - they do NOT require conscious or voluntary input
51
Exaggerated (hyper-reflexive) reflexes are often observed with (LMN/UMN) lesions. A reduced/diminished or absent reflex indicates (LMN/UMN) lesions.
UMN | LMN
52
What does the extensor reflex test?
The radial nerve function of the forelimb
53
How do you perform the extensor reflex test?
Place the animal in lateral recumbency Place a hand under the foot With the limb positioned in extension and push it gently
54
What is the normal reflex for the extensor reflex?
For the animal to push back against your hand
55
What extensor reflex response is indicative of LMN disease? UMN disease?
LMN disease - decreased or absence of resistance | UMN disease - Increased tone of the triceps muscle
56
How is the panniculus reflex done?
Apply pressure on the cutaneous trunci starting caudally and move forward
57
The reflex arc for the panniculus reflex is the sensory fibers from each dermatome enters the spinal cord and then ascends to the ___ and ___ segments.
C8 and T1
58
How do you perform the withdrawal reflexes?
Apply adequate force and pinch the interdigital skin as well as the coronary band of each individual claw.
59
What do the withdrawal reflexes require to be intact for the front limbs?
C6-T2 and the axillary, median, and ulnar nerves
60
What do the withdrawal reflexes require to be intact for the back limbs?
L 5(6)- S1 and the sciatic nerve in the hind limb
61
T/F: A cross extensor reflex can be normal in neonates but in mature ruminants it can indicated interference with the normal UMN pathways.
True
62
What does the patellar reflex require to be intact?
L4, L5, and the femoral nerve
63
What is the normal response to the patellar reflex?
Obvious and repeatable extension of the stifle
64
What can cause an exaggerated patellar reflex response?
Both UMN damage and sciatic nerve damage
65
What causes decreased patellar reflex responses?
Lesions of L4, L5, the femoral nerve, and myonecrosis and white muscle disease
66
How is the perineal reflex done?
Pinching of the skin around the rectum
67
What is required for an intact perineal reflex?
Intact spinal cord segments S2-S4 and the pudendal and caudal rectal nerves
68
How is cerebrospinal fluid collected?
Palpate the hooks/wing of the ileum, and feel for depression slightly caudal to an imaginary line drawn in between the hooks. The spinal needle is placed in the lumbosacral space to the subarachnoid space
69
What is the rule of thumb for the amount of cerebrospinal fluid that can be collected?
Approximately 0.5 ml per 5 kg of body weight can safely be removed
70
What should normal cerebrospinal fluid look like?
Clear and colorless
71
What is cloudy or turbid cerebrospinal fluid indicative of?
Increased white cell concentration
72
What does a stable foam in cerebrospinal fluid indicate?
Icnreased protein concentration
73
What are normal WBC and protein levels in cerebrospinal fluid in cattle?
< 3 WBC/dL | < 30 mg/dl protein
74
What is the normal specific gravity of cerebrospinal fluid?
<1.010
75
Define depression.
Decreased responsiveness to stimuli
76
Define stupor.
Animal appears to be sleeping when undisturbed; mild stimuli will not induce arousal, but vigorous stimuli will induce arousal
77
Define coma.
An unconscious state in which spinal reflexes can be normal, but vigorous noxious stimuli does not induce arousal
78
Define seizure.
Involuntary episode of muscular activity that may be generalized or localized If generalized - the animal becomes recumbent, has altered mentation, and has periodic episodes of muscular activity
79
Define opisthotonus.
Dorsiflexion of the head and neck
80
Define nystagmus.
Inappropriate and involuntary movements of the eyes; can be horizontal, vertical, rotary, or intermittent
81
Where does the fast component of nystagmus typically point? Slow?
Fast - away from the side of the lesion | Slow - towards the side of the lesion
82
Define intention tremor.
Inappropriate loss of fine motor control, particularly when the animal intends to eat or nurse
83
Define a tremor.
Small and rapid altering contractions of agonist and antagonist muscle groups that occur at rest or during movement
84
Define weakness.
Loss of muscle strength
85
Define paresis.
Partial loss of neural control of muscles
86
Define paralysis.
Complete loss of neural control of the muscles
87
Define proprioception.
Awareness of the location of the limb in space
88
Define circumduction.
Movement of a limb such that the distal portion describes a circle, with the proximal portion being fixed
89
Define ataxia.
Abnormal gait characterized by incoordination but without spasticity, weakness, or involuntary movements
90
What causes atexia?
Lesions in the proprioceptive pathways, vestibular system, or cerebellum
91
Define dysmetria.
Movements that are too short or too long
92
Define hypermetria.
The exaggerated movements of the limbs during locomotion; goose-stepping
93
If there is a lesion at C1-C5, what deficits will there be? Reflexes present?
UMN on all 4 limbs Spastic paresis of both front and back limbs Hyperactive to normal reflexes in all 4 limbs
94
If there is a lesion at C6-T2, what deficits will there be? Reflexes present?
UMN hindlimbs, LMN front limbs Spastic paresis of back limbs Flacid paresis of front limbs Neurogenic muscular atrophy of front limbs only Hyperactive to normal reflexes in rear limbs Hypoactive reflexes in front limbs
95
If there is a lesion at T3-L3, what deficits will there be? Reflexes present?
``` UMN hindlimbs only Spastic paresis of back limbs Normal back limbs No neurogenic muscle atrophy Hyperactive to normal reflexes in hind limbs ```
96
If there is a lesion at L4-sacrum, what deficits will there be? Reflexes?
``` LMN hindlimbs only Flaccid paresis of hind limbs Normal thoracic limbs Neurogenic muscular atrophy in hindlimbs Hyporeflexive in hind limbs ```
97
What lesion would result in a flaccid bladder that is distended, abnormally large, and atonic urethral sphincter?
Sacral lesion S1 and S2
98
What lesion would result in a hypertonic bladder that has increased tone, high pressure, and a hypertonic urethral sphincter?
Lesion cranial to S1

LA Clinical Medicine (33 decks)

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