unit 8 Flashcards

1
Q

Main hormone product of the testes:

A

Testosterone

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1
Q

Main hormone product of the ovaries:

A

Estradiol
Progesterone

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2
Q

The exception to negative feedback of gonadal steroids at the hypothalamus and anterior pituitary

A

Sustained high levels of estradiol trigger a surge of LH/FSH

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3
Q

Cholesterol- _____ - ______ - _______ - DHT

A

Progesterone
Adione
Testosterones

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4
Q

Why are the testes away from the body?

A

Sperm needs to be 2-3 degrees less warm than the body temperature

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4
Q

What is the condition when testes fail to descend?

A

cryptorchidism

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4
Q

Where is the epididymis located?

A

Above the testes

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4
Q

The journey of sperm from the testes

A

Seminiferous tubules
Epididymis
Vas deferens
Seminal vesicle
urethra

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5
Q

___ cells are located in the interstitium of the seminiferous tubules, the ____ cells are located in the tubule

A

Leydig
Sertoli

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6
Q

Leydig cells make ______

A

Androgens (testosterone)

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7
Q

Sertoli cells ______ spermatogenesis

A

Coordinate

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8
Q

Spermatogonia cells are ____

A

Mitotic

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9
Q

When spermatogonia cells enter meiosis they are called _____ in meiosis 1, _____ in meiosis 2 and _____ when they have completed meiosis but not remodeling

A

Primary spermatocyte
Secondary spermatocyte
spermatid

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10
Q

Primordial follicles have three parts:

A

Oocyte surrounded by a single layer of granulosa cell precursors covered in basal lamina

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11
Q

A primary follicle has an enlarged _____ and the granulosa cells ___________

A

Oocyte
Begin to divide but are still SINGLE LAYER

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12
Q

Secondary follicles develop ____; a layer of cells outside the _________

A

Theca
Basal lamina

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13
Q

The corpus luteum is formed from the ________

A

Ruptured follicle

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14
Q

Primordial follicle - ________ - _________ - _________ - _______ - ________

A

Primary follicle
Secondary follicle
Mature follicle
Ovulated oocyte
Corpus luteum

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15
Q

The surge of _____ causes ovulation

16
Q

The rise of estrogen concentration occurs in the _____ phase

A

Proliferative

17
Q

sustained high levels of _____ cause surge of ___

A

estrogen
LH hormone

18
Q

The corpus luteum secretes mainly ______ and some _____ during the _____ phase of the cycle

A

Progesterone
estrogen
Secretory

19
Q

High levels of progesterone and estrogen cause _________ feedback with growth hormones LH and FSH

A

Highly negative

20
Q

The commitment to male or female gonad is regulated by ____ (___________) which is expressed by ______

A

Sry
Master transcription factor
Pre-Sertoli cells

21
When someone lacks Sry they will have ______ gonads
Female
22
The duct work of gamete transportation IN MALES is regulated by _________ from _______ that act on the ________ duct and ___________ from _______ which causes regression of _________ duct
Testosterone Leydig cells wollfian Anti-mullerian hormone Sertoli cells Mullerian
23
The duct work of gamete transportation IN FEMALES is regulated by ______________
Lack of testosterone or anti-mullerian hormone, default to female
24
What is the signal to form external female genitalia?
Absence of a signal
25
The signal to form MALE external genitalia is ______ from ____ cells which must be in the ____ form
Testosterone Leydig DHT
26
Individuals that lack the 5a-reductase will prevent ____________ because _______
Formation of male external genitalia Testosterone cannot convert to DHT
27
If a male has loss of function for androgen receptors what will happen?
No testes decent No wollfian ducts Mullerian ducts retained
28
Stretch of vaginal canal causes signaling through the _____ which causes release of _____ which then stimulates ________
CNS oxytocin Uterine contractions
29
The parturition has a positive feedback reflex involving _________from the ___________
Oxytocin Posterior pituitary
30
During the parturition there will be cervical _______, rhythmic __________, _____ of baby, _______ of the placenta
Softening Uterine contractions Delivery Expulsion
31
Trophectoderm will give rise to ________
Extra-embryonic membranes
32
Inner cell mass will give rise to ___________
Embryo proper
33
The first differentiated cell types in mammalian embryos are:
Inner cell mass Trophectoderm
34
Fertilization of the egg occurs in the ________
Fallopian tube (ova duct)
35
If a male has loss of function for androgen receptors what will happen?
No testes decent No wollfian ducts Mullerian ducts retained
36
Individuals that lack the 5a-reductase will prevent ____________ because _______
Formation of male external genitalia Testosterone cannot convert to DHT
37
The signal to form MALE external genitalia is ______ from ____ cells which must be in the ____ form
Testosterone Leydig DHT
38
What is the signal to form external female genitalia?
Absence of a signal
39
The duct work of gamete transportation IN FEMALES is regulated by ______________
Lack of testosterone or anti-mullerian hormone, default to female
40
The duct work of gamete transportation IN MALES is regulated by _________ from _______ that act on the ________ duct and ___________ from _______ which causes regression of _________ duct
Testosterone Leydig cells wollfian Anti-mullerian hormone Sertoli cells Mullerian
41
When someone lacks Sry they will have ______ gonads
Female
42
The commitment to male or female gonad is regulated by ____ (___________) which is expressed by ______
Sry Master transcription factor Pre-Sertoli cells