Uworld 1 Flashcards

(30 cards)

1
Q

Pineal gland tumor features

A
limited upward gaze
upper eyelad retraction
pupillary abnormalities
papilledema
HA
Vomiting
Ataxia
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2
Q

Transposition of great vessels x-ray and cardio findings

A

single s2
+- vsd
narrow mediastinum

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3
Q

Tetrology of fallot findings

A

harsh pulmonic stenosis murmur(systolic)
VSD
Boot shaped heart
Big RV

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4
Q

Tricuspid atresia findings

A

single s2
VSD
minimal pull flow

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5
Q

Truncus arteriosus findings

A

single s2 systolic ejection murmur

increased pulmonary blood flow and edema

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6
Q

cysteine stone

A

radiolucent, peds/teen,hexagon crystal,+nitropruside test

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7
Q

CHARGE syndrome

A
Colboma(hole in the eye-word pupil
Heart (TOF/VSD)
Atresia
Retardation
Genitourinary abnormalities
Ear-shape and function
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8
Q
Beckwith /wiedman Syndrome 
Path
Exam
Complications
Surveillance
A

Deregulation of imprinted gene expression in chrome 11p15
exam: macrosomia, rapid growth, omphalacle or jumbo hernia, macroglossia, hemihyperplasia
Complications: wilms tumor, hepatoblastoma
Surveillance:AFP, Abdominal ultrasound

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9
Q

what markers are elevated in choriocarcinoma

A

CA19-9, CEA

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10
Q

Chromium Def sx

A

impaired glucose control

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11
Q

Copper deficiency sx

A
Brittle Hair
Skin depigmentation
Anemia
ataxia
peripheral neuropathy
Osteoporosis
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12
Q

selenium deficiency sx

A

Thyroid dysfunction
cardiomyopathy
immune dysfunction

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13
Q

zinc deficiency sx

A
Alopecia
Pustular skin rash 
Hypogonadism
Impaired wound healing
immune dysfunction
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14
Q

Methotrexate MOA and Adverse Events

A

Folate inhibition’s

  • hepatotoxicty
  • stomatitis
  • cytopenias
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15
Q

Hydroxychloroquine MOA

SE

A

TNF & IL1 supressor

-retinopathy

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16
Q

Sulfasalzine MOA, SE

A

TNF, IL-1 supressor

-hepatotoxicty
stomatitis
Hemolytic anemia

17
Q

TNF alpha inhibitors SE

A

infection
demyelination
congestive 💜 failure
malignancy

18
Q

Diverticulitis + urine findings

A

LLQ pain
nausea and vomiting
+Leuk, - nitrate

19
Q

Rocky Mountain Spotted fever labs

A

⬇️ platelets,⬇️ Na,⬆️ ast/alt

20
Q

Rocky Mountain Spotted fever tx

21
Q

Risk factors for placenta previa

A

previous c section
prior previa
multiple gestations
prior uterine surgery

22
Q

infertility tx PCOS after weight loss

A

Letrozole-aromatase inhibitor

23
Q

what increases t4 binding globulin

24
Q

electrolyte abnormality multiple myeloma

25
Granulose cell. tumor marks
Estradiol/inhibin
26
HUS triad
Hemolytic anemia Thrombocytopenia Acute kidney injury
27
what causes HELLP
Distention of liver capsule
28
2nd most important lifestyle change HTN
DASH diet
29
Paroxsymal noctural hemoglobinuria
``` Hemolysis fatigue increased risk for venous thrombosis no CD55 or 59 Tx=iron and folate, eculizumab ```
30
Sarcoid neuro sx
Facial nerve palsy Central DI Hypogonadotropic Hypogonadism ⬆️ Ca2+