week of 5/4

Question 1

Congenital CMV clinical features

Answer 1

Growth restriction
microcephaly
periventricular calcifications 
hepatosplenomegaly 
thrombocytopenia

Question 2

phototherapy bilirubin levels 4 day old

Answer 2

> 20

Question 3

exchange transfusion level for hyper bile 4 day old

Answer 3

> 25

Question 4

head bleeding that crosses suture line after forceps delivery what vessel

Answer 4

subgaleal

Question 5

Test for chronic granulomatous disease

Answer 5

Dihydrorhodamine 123 test
nitro blue tetrazolium test
(both test neutrophil function)

Question 6

chronic granulomatous disease sx

Answer 6

recurrent skin and lung accesses .

XLR

Question 7

chronic granulomatous disease pathophys

Answer 7

no phagocytic oxidative burst = neutros don’t work

Question 8

Serum sickness like reaction sx

Answer 8

fever, rashm polyarthralgia 1-2 weeks after exposure

Question 9

serum sickness like reaction causes

Answer 9

Immune complex formation
antibiotics
Acute hep b

Question 10

what hormone surge causes referring syndrome

Answer 10

insulin

Question 11

tx for radial head sublimation (nurse maids elbow)

Answer 11

hyper pronation of forearm/supination of forearm and flexion and elbow

Question 12

meds that cause idiopathic intracranial hypertension.

Answer 12

retinoids, tetracyclines, growth hormones.

obese women of child bearing age also get it

Question 13

hereditary specherocytocis test

Answer 13

Eosin 5 maleimide binding
or acidified glycerol test
osmotic fragility- less sensitive but more commonly used

Question 14

most common heart thing trisomy 18

Answer 14

VSD

Question 15

Waterhouse Friderichsen sundry

Answer 15

fulminant meningococcemia, purpura, vaso motor collapse , adrenal gland failure

Question 16

potter’s sequence kidney problem

Answer 16

posterior urethral valves

Question 17

ALL sx

Answer 17

brusing, bleeding gums
contender lymphadenopathy
hepatosplenomegaly

Question 18

Friedrich ataxia sx

Answer 18

neuro dysfunction
cardiomyopathy
diabetes
scoliosis of other spine stuff

Question 19

Meds to avoid with G6PD

Answer 19

Dapsone
Isobutyl nitrite
nitrofurantoin
primaquine
rasburicase

Question 20

primary amenorrhea, uterus present, next test

Answer 20

FSH

Question 21

Di Gerorge Pneumonic

Answer 21

C ardiac defects (truncal, tet of fallot)
Abnormal facies(ears
Thymic aplasia
Craniofacial abnormalities 
Hypocalcemia/hypoparathyroid
22(chromosome)

Question 22

what causes CHRONIC joint pain in hemophillia

Answer 22

Hemosiderin deposition and fibrosis

Question 23

acute glacoma test if no gonioscopy available

Answer 23

tonometry

Question 24

pemphigus vulgaris immunofluorescence

Answer 24

netlike IgG

Question 25

what is a protein gap and what condition has it

Answer 25

total protein-albumin >4, multiple myeloma

Question 26

multiple myeloma sx

Answer 26

``` Hypercalcemia Renal failure protein gap normocytic anemia clonal plasma cell proliferation ```

Question 27

When to add sterioids to Pneumocystis tx

Answer 27

paO2 <70 A-a > 35 of pulse ox less than 92%

Question 28

How do immunosuppressants cause AKI

Answer 28

Arteriolar vasoconstriction

Question 29

what electrolyte most likely low refeeding

Answer 29

phosphorus | look for hypo k also

Question 30

expanding neck hematoma tx

Answer 30

drain, cricothyrotomy if that doesn't work.

Question 31

what is psoas sign

Answer 31

abdominal pain with hip extension

Question 32

what electrolyte abnormality can bactrim cause

Answer 32

hyperkalemia, blocks sodium channels in collecting tubules

Question 33

what meds does uworld say causes SIADH

Answer 33

Carbamazepine SSRI NSAIDS

Question 34

what class is amikacin

Answer 34

aminoglycoside

Question 35

serious complication of aminoglycocides

Answer 35

Acute renal failure

Question 36

EPO side effect

Answer 36

Hypertension, watch out for crisis