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Flashcards in UWorld-Embryology/Development Deck (7)
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50% of Down's syndrome patients have congenital heart abnormalities. What is the most common kind of heart abnormality?

endocardial cushion defects


during the second trimester where is most of the progesterone produced

the placenta takes over progesterone production in the second and third trimesters


what inhibits lactation (despite rising prolactin levels) and develops the breast tissue during pregnancy

progesterone and estrogen


what is Von Recklinghausen's disease and what are its commonest clinical manifestations

neurofibromatosis type 1: neurofibromas, optic nerve gliomas, Lisch nodules (pigmented nodules of the iris), and cafe au lait spots


what is Osler-Weber-Rendu syndrome

hereditary hemorrhagic telangiectasia: an inherited disorder of blood vessels leading to telangiectasias, epistaxis, skin discolorations, AVMs, GI bleeding and hematuria


what's the other name for Sturge-Weber syndrome and what are its common clinical manifestations

encephalotrigeminal angiomatosis:
causes cutaneous angiomas (such as port-wine stain in trigeminal dermatome), leptomeningeal angiomas, seizures, mental retardation, hemiplegia, tram-track calcifications on radiology


what will exert the greatest effect on achieving a lecithin-to-sphingomyelin ratio greater than or equal to 2

cortisol helps the fetal lungs develop; lecithin-to-sphingomyelin ratio greater than or equal to 2 indicates fetal lung maturity