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Flashcards in UWorld-Embryology/Development Deck (7)
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1

50% of Down's syndrome patients have congenital heart abnormalities. What is the most common kind of heart abnormality?

endocardial cushion defects

2

during the second trimester where is most of the progesterone produced

the placenta takes over progesterone production in the second and third trimesters

3

what inhibits lactation (despite rising prolactin levels) and develops the breast tissue during pregnancy

progesterone and estrogen

4

what is Von Recklinghausen's disease and what are its commonest clinical manifestations

neurofibromatosis type 1: neurofibromas, optic nerve gliomas, Lisch nodules (pigmented nodules of the iris), and cafe au lait spots

5

what is Osler-Weber-Rendu syndrome

hereditary hemorrhagic telangiectasia: an inherited disorder of blood vessels leading to telangiectasias, epistaxis, skin discolorations, AVMs, GI bleeding and hematuria

6

what's the other name for Sturge-Weber syndrome and what are its common clinical manifestations

encephalotrigeminal angiomatosis:
causes cutaneous angiomas (such as port-wine stain in trigeminal dermatome), leptomeningeal angiomas, seizures, mental retardation, hemiplegia, tram-track calcifications on radiology

7

what will exert the greatest effect on achieving a lecithin-to-sphingomyelin ratio greater than or equal to 2

cortisol helps the fetal lungs develop; lecithin-to-sphingomyelin ratio greater than or equal to 2 indicates fetal lung maturity