Virus, Hepatitis and Herpes (complete) Flashcards Preview

DMD 5245 > Virus, Hepatitis and Herpes (complete) > Flashcards

Flashcards in Virus, Hepatitis and Herpes (complete) Deck (51)
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1

What is the classification for Herpesviridae

DNA
Icosahedral
Enveloped
Double Stranded (linear)

2

What are the strains of Herpes virus found in the oral cavity

HSV-1 (Herpes Simplex Virus)
HSV-2
EBV (Epstein-Barr virus)
CMV (Cytomegalo Virus)

3

Where are HSV-`1 infections usually found

in HSV infections above the waist

4

where are HSV-2 infections usually found

in HSV infections below the waist

5

Are Herpes infections often latent infections

yes

6

What are the 8 human herpes viruses

Herpes Simplex Virus-1 (HSV-1) HHV-1
Herpes Simplex Virus-2 (HSV-2) HHV-2
Varicella zoster Virus (VZV) HHV-3
Epstein-Barr Virus (EBV) HHV-4
Cytomegalo Virus (CMV) HHV-5
Herpes Simplex Virus-6 HHV-6
Herpes Simplex Virus-7 HHV-7
Herpes Simplex Virus-8 HHV-8

7

Where are HSV-1 and HSV-2 located in the human body

in the nerve ganglia

8

where is EBV found in the human body

in resting B cells

9

Where is CMV found in the human body

in the salivary glands??

10

Who is most susceptible to primary herpes

6 month to 6 year old children (adults are not very susceptible, except as STD)

11

What is caused by primary herpes

Gingivostomatitis

12

how many adults are Ab + to primary herpes

80%

13

how is primary herpes transmitted

saliva, kissing, close contact, fomites (toys)

14

how does primary herpes express on skin

excema, whilow, herpes gladitorum

15

how does primary herpes express on the cornea

keratojunctivitis

16

What type of herpes causes cold sores and fever blisters

HSV-1

17

Is ocular herpes primary herpes, or reactivation of latent herpes

reactivation of latent herpes

18

What happens to Herpes viridae after primary gingivostomatitis

the virus hangs out in the Trigeminal ganglion, then can be reactivated in the maxillary, mandibular and opthalmic branches of the nerve

19

What causes Herpes to reactivate

stress, excessive sunlight, fever, trauma, immunosuppression

20

What is the main difference between the infection steps of Herpesviridae and other viruses

Herpes viridae blocks the

21

What can secondary herpes virus cause

Blindness
Meningoencephalitis
Fulminant HSV
Transfer to fetus upon birth
whitlow
herpes gladitorum
pharyngitis, autoinoculation
loss of bladder control
pyschological trauma
interrupted personal relationship
stillbirths, spontaneous abortions

22

What does EBV cause

burkitt's lymphoma
hodgkins disease

23

how does an EBV infection differ from first to third world countries

in third world it is mostly asymptomatic
in the first world it is a delayed infection, infectious mononucleosis

24

How does EBV get transmitted

salivary droplets, oral-respiratory

25

where does the EBV replicate

in nasopharynx and salivary glands

26

What are the symptoms of an EBV? (mono)

Sore throat, malaise, fever-chills, headache, anorexia, profound fatigue

27

What is the most susceptible age group to EBV infection

18-22 years old

28

What do we do for EBV infections

we don't have a vaccine, and it is not sensitive to chemotherapy

29

What causes chicken pox

HHV-3 (VZV)

30

how does chicken pox relate to shingles

chicken pox is the is the primary infection HHV-3, shingles is the reactivation of that HHV-3 infection