Wound, Bone and Joint Infection

Question 1

What are the major pathogens causing SSI

Answer 1

S aureus
E coli
P aeroginosa

Question 2

What can you treat MRSA with

Answer 2

IV Linezoid

Question 3

What are RF for septic arthritis

Answer 3

Rheumatoid arthritis 
Osteoarthritis 
Joint prosthesis 
IVDU
Diabetes, chronic renal disease, chronic liver disease

Question 4

What are the main causative organisms for septic arthritis

Answer 4

Stapj aureus

Strep (pyogenes, pneumonia) 
Gram neg (e coli, h influenzas)

Question 5

What is the history of septic arthritis

Answer 5

1-2 wk history of red painful swollen joint
restricted movement
monoarticular
knee involved in 50%

Question 6

How do you ix septic arthritis

Answer 6

1. Blood cultures (BEFORE antibiotics)
2. Synovial fluid aspiration & MC&S
3. ESR, CRP
   USS (confirms effusion, aspiration)
   CT (erosive bone change)
   MRI (joint effusion, cartilage destruction)

Question 7

What is the main pathogen causing vertebral osteomyelitis

Answer 7

s aureus

Question 8

How does vertebral osteomyelitis occur

Answer 8

acute haematogeneous spread

implantation during disc surgery

Question 9

What is location of vertebral osteomyeklitis

Answer 9

LUMBAAR

Question 10

What are symptoms of vertebral osteomyelitis

Answer 10

back pain
fever
neuro impairment

Question 11

How do you investigate vertebral osteomyelitis

Answer 11

MRI
Blood culture
Ct guided / open biopsy

Question 12

How do you treat vertebral osteomyelitis

Answer 12

6 week antibiotic course

Question 13

What is the most common organism in prosthetic joint infection

Answer 13

COAG NEGATIVE STAPHYLOCOCCI (more than S aureus)

and other gram + cocci (strep, enterococci)

Question 14

How do you diagnose PJI

Answer 14

Radiology (loosening)

CRP elevated +Joint aspiration