Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Path - Micro > STI > Flashcards

STI Flashcards

1
Q

What STIs present as discharge

A 
Gonorrhoea 
Chlamydia 
Trichomonas 
Candida 
BV
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What STIs present as ulcer

A 
Syphilis 
HSV
LGV 
Chancroid 
Donovanosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What STIs present as growths/lumps

A

Genital warts, HPV
Molluscum

Scabies
Pubic lice

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What causes PAINFUL genital ulcers

A

HSV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What causes PAINLESS genital ulcers

A

syphilis

lymphogranuloma venereum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What can gonorrhoea cause in the neoonate if maternal gonorrhoea is untreated

A

Opthalmia neonatorum (neonatal conjunctivitis)

via transfer in birth canal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What can gonorrhoea cause in complement deficient patient

A

DIsseminated gonococcal infection > septicaemia, rash, arthritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

how does gonorrhoea present

A

urethritis
cervicitis
proctitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What can you do for diagnosis of gonorrhoea

A

vaginal/urethral/rectal smear

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How do you manage gonorrhoea

A

Ceftriaxone IM 250mg

OR

Cefixime PO 400mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What do Chlamydia serovars A,B,C cause

A

TRACHOMA (infection of the eye > blindness9

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What do chlamydia serovars D-K cause

A

genital chlamydia infection OR opthalmia neonatorum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What do chlamydia serovars L1,L2,L3 cause

A

lympho-granuloma venereum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

How do you diagnose chlamydia

A

NAAT (Nucleic Acid Amplification Test)

from genital swab (F) or urine (M)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How do you treat uncomplicated chlamydia

A

Doxycycline 100mg BD 7/7

OR

azithromycin 1g STAT

OR

Erythromycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is LGN

A

Lympho Granuloma Venereum

Lymphatic infection with Chlamydia Trachomatis, from serovars L1,L2,L3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Explain early LGV (1st stage)

A

Lasts 3-12 days
Genital ulcer - painless, non-indurated
Balanitis, proctitis, cervicitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Explain the second stage of early LGV

A

inguinal buboes: painful, 2/3 unilateral, may rupture, fever, malaise

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Explain late LGV

A 
Ingunial lymphadenooathy 
abscess formation 
genital elephantitis  
genital ulcers
frozen pelvis 
rectal strictures
perirectal abscesses
lymphorroids
20
Q

Explain current LGV outbreak

A

rectal symptoms: tenesmus, pain, bleeding, mucous discharge

21
Q

How do you diagnose LGV

A

NAAT
Chlamydia confirmed on PCR (2 platforms)
Genotypic identification of L1,L2,L3

22
Q

How do you manage LGV

A

Doxycyline 100mg BD for 21/7

23
Q

What microscopy can you do for syphilis

A

Swab ulcer >

Dark ground microscopy

24
Q

What investigation do you do for syphilis PRIMARY

A

swab ulcer, then microscopy (dark ground)

25
Q

what investigation do you do for syphilis SECONDARY

A

Antibody detection

26
Q

what does VDLR slide test detect

A

Lipoidal antibody on both host and treponemal cells

Risk of false positives, as reagemnts contain cardiolipin, lethicin, cholesterol

27
Q

What is the problem with antibody detection in syphilis

A

remains positive for many years

so it is not good at confirming if treatment has worked

28
Q

How does primary syphilis present

A

CHANCRE

  • Macule > papule > indurated painless genital ulcer 1-12 weeks after tranmission
  • Clean base, solid exhudate

+ regional lymphadenopathy

29
Q

How long after primary infection does primary syphilis last

A

4-6 weeks

30
Q

Explain symptoms of secondary syphilis

A

systemic bacteraemia
low grade fever, malaise
Symmetrical, non-pruritis maculopapular rash on back, trunmk, arms, legs, palms, soles
Mucosal lesions

Uveitis, choroidoretinitis
Alopecia
Snail track oral ulcers
Condyloma acuminate (genital warts)

31
Q

What are sx of latent syphilis

A

NONE - asymptomatic

32
Q

What are sx of tertiary syphilis

A

Gummaa (granuloma)
CV (aortitis, ++ spirochaetes, ++ inflammation)
Neurosyphilis
Argyl RObertson pupul

33
Q

What is Argyl RObertson pupil

A

aka prostitute pupil

accomodates but does not react

34
Q

How do you manage syphilis

A

single dose IM Benzathine Penicillin

35
Q

What is a risk after treating syphilis, and how do you manage it

A

Jarish Heimer Reaction

  • fever
  • headache
  • myalgia
  • exacerbation of syphilitis symptoms

Self resolves within 24h, so no need to treat

36
Q

What investigation do you do for chancroid (haemophilius ducreyi)

A

Culture on chocolate agar

37
Q

What does donovanosis cause

A

Granuloma inguinale

38
Q

Where does donovanosis occur geographically

A

Africa, India, PNG, australia

39
Q

explain donovanosis symptoms

A

large expanding ulcer starting as papule / nodule > breaks down > beefy red appearance

40
Q

How do you investigate trichomoniasis

A

wet prep microscop, PCR

41
Q

What is the cause of BV

A

abnoirmal vaginal flora, polymicrobial, low lactobacilli

Sexually associated, not transmitted

42
Q

How do you manage candidiasis

A

Clotrimazole (topical)

Fluconazole (oral)

43
Q

What presentation of molluscum indicates HIV

A

FACIAL molluscum

44
Q

What is clinical tx for genital warts

A

cryotherapy

2nd line: imiquimod

45
Q

what is home tx for genital warts

A

podophyllotoxin solution/cream

Path - Micro (20 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions