1. Healthing and Repair Flashcards Preview

T3- Patho unit 1 > 1. Healthing and Repair > Flashcards

Flashcards in 1. Healthing and Repair Deck (24):
1

Def of repair:

replacement of a damaged tis by a new healthy one

2

______: replacement of injured cells by new PARENCHYMAL cells of the same type by division of adjacent ones

regeneration (restitution)

3

_____: replacement of lost tis by scar formation

organization

4

cells of the body can be divided int 3 groups according to their regenerative capacity

1. labile
2. stable
3. permanent

5

Name (3) labile cells

1. epithelial cells
2. crypt cells of gut mucosa
3. hematopoietic stem cells

6

___ cells normally divide actively throughout life

labile cells

7

___ cells have a long life span--> very slow rate of division

stable cells

8

___ cells remain in intermitotic phase for long periods, retain capacity to enter the mitotic cycle when needed

stable cells

9

__cells can be in the form of ___ cells in solid organs or ___ cells (such as blasts & cytes)

parenchymal
mesenchymal

10

___ will form when the CT framework is destroyed

scar formation

11

Regeneration occurs when ____ parenchymal cells remain & _____ in the area of necrosis

enough viable

INTACT CT framework in the area

12

Nmae 3 permanent cells

Neurons
myocardial cells
skeletal M cells

(they have no capacity for mitotic division in post natal life)

13

Scar tis replaces the tiss in the injured area by ____ tiss

granulation tis

14

4 Things that occur during scar formation

1. replaced of injured area by grandulation tiss
2. loops of cap surrport the myofibroblasts
3. inflam cells
4. actively contracts to reduce wound size

15

3 types of wounds

1. abrasion
2. incision & laceration
3. wounds with epidermal defect

16

_____ wound is the removal of superficial part of epidermis . Regenerate without scaring

abrasion wound

17

Basal cell layer (___ cell) regenerate the epithelium without scaring during abraasion wounds

labile

18

Incision is a ____ wound

cute

19

Laceration is a ___ wound

tearing

20

Both epidermis and dermis are involved during (2) wounds

incision (cut)
laceration (tear)

21

______ would: has rapid healing. There is no infection, no foreign mat. and minimal tis loss

1st intention

22

Wounds with epidermal effect loss large areas of epidermis and has necrosis of underlying dermis. Ex___ & ___

burns and crush injuries

23

_____ intention: is a wound with epidermal defects

2nd intention

24

(5) causes of defective wound healing

1. failure of syn of collagen fibers
2. excessive collagen production
3. local factors
4. Diabetes mellitus
5. Excessive levels of corticosteroids